Trousseau's Syndrome Presenting as Multiple Cerebral Infarctions Caused by Mucin-producing Bladder Micropapillary Urothelial Cancer |
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| Authors: | Sho Shimohama Koichi Oki Hidefumi Narita Kyoko Mashima Satoshi Yamada Tomohide Adachi Yosuke Kobayashi Shigemichi Hirose Haruhiko Hoshino |
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| Institution: | 1.Department of Neurology, Tokyo Saiseikai Central Hospital, Japan; 2.Department of Surgery, Tokyo Saiseikai Central Hospital, Japan; 3.Department of Pathology, Tokyo Saiseikai Central Hospital, Japan |
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| Abstract: | We herein report a 70-year-old man with recurrent multiple cerebral infarctions under warfarin therapy who was finally diagnosed with Trousseau''s syndrome resulting from advanced bladder cancer. A histological examination of the mesenteric lymph nodes revealed metastasis of micropapillary urothelial cancer with positive mucin markers CA125 and MUC1. Blood examinations also indicated elevated tumor markers, such as CA19-9 and CA125. To our knowledge, this is the first report of Trousseau''s syndrome in a patient with bladder micropapillary urothelial cancer in which mucin involvement was clearly proven by histological and serological examinations. |
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| Keywords: | Trousseau''s syndrome bladder cancer cerebral infarction micropapillary urothelial cancer mucin |
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