| 精神分裂症患者的脑功能显像与神经心理测验的相关研究 |
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| 引用本文： | 李星宝,吴志兴.精神分裂症患者的脑功能显像与神经心理测验的相关研究[J].中国临床心理学杂志,1996,4(3):135-138. |
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| 作者姓名： | 李星宝 吴志兴 |
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| 作者单位： | 山东省精神卫生中心，山东省立医院核医学科 |
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| 摘 要： | 本研究应用单光子发射断层摄影术（ＳＰＥＣＴ）、ＨＲ成套神经心理测验（成人）修订本［ＨＲＢ（Ａ）－ＲＣ］和修订韦氏记忆测验（ＷＭＳ－ＲＣ）对３２例住院精神分裂症患者的脑功能改变及脑功能显像与神经心理测验之关系进行探讨。结果显示，精神分裂症患者存在额叶、颞叶和基底节的脑血灌流量降低，同时表现程度不同的神经心理功能损害，此改变在阴性症状和阳性症状的病人间无差异。脑血灌流量降低与损伤指数（ＤＱ）和记忆商数（ＭＱ）未见明显关系。相关分析表明，ＤＱ与ＴＥＳＳ评分呈显著正相关（ｒ＝０．３６，Ｐ＜０．０５）；ＭＱ与住院次数（ｒ＝－０．４２，Ｐ＜０．０５）、ＢＰＲＳ评分（ｒ＝－０．５６，Ｐ＜０．０１）、ＳＡＰＳ评分（ｒ＝－０．３９，Ｐ＜０．０５）和ＳＡＮ评分（ｒ＝－０．３７，Ｐ＜０．０５）呈显著负相关，与ＧＡＳ评分（ｒ＝０．５３，Ｐ＜０．０１）呈显著正相关
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| 关 键 词： | 精神分裂症 脑功能显像 神经心理测验 |
The Relationship between Cerebral Blood Flow and Neuropsychological Functioning in Schizophrenia. |
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| /Li Xingbao et al,Shangdong Mental Health Centre,Jinan.The Relationship between Cerebral Blood Flow and Neuropsychological Functioning in Schizophrenia.[J].Chinese Journal of Clinical Psychology,1996,4(3):135-138. |
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| Authors: | /Li Xingbao Shangdong Mental Health Centre Jinan |
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| Abstract: | To explore the relationship between cerebral blood flow and neuropsychological function, 32 schizophrenic patients were investigated with single photon emission computed tomography(SPECT), HRB(A)-RC and WMS-RC. Results showed that regional cerebral blood flow decreased significantly in the frontal lobes, temporal lobes and basal ganglia. DQ increased and MQ decreased. DQ was positively correlated with TESS score. Although MQ was positively correlated with GAS score, it was negatively correlated with the number of hospitalization and the scores of BPRS, SANS and SAPS. |
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| Keywords: | Schizophrenia Neuropsychological test SPECT |
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