急性白血病免疫标记研究的重要意义——附65例病例分析

我们利用APAAP技术对65例急性自血病做了免疫表型分析。其中包括20例急性淋巴细胞白血病(ALL),43例急性非淋巴细胞自血病(ANLL)及2例混合性急性自血病(HAL)。根据ALL白血病细胞表型的表达,将其分成了4个亚型;C- T-,N-和B-ALL。仅借助于形态学检查是不易诊断HAL的,同时也常常难以将ANLL的M_1同ALL(L_1和L_2)区别开来。本组研究的结果表明免疫表型的分析有助于ANLL和HAL的诊断。我们认为,免疫表型分析使白血病的诊断和分型更趋于完善。

Immunophenotypic Studies on Acute Leukemia:An Analysis of 65 Cases

Immunophenotypic analysis was performed by APAAP technique in 65 patients with acute leukemia, including 20 cases of acute lymphoid leukemia (ALL), 43 cases of acute nonlymphoblastio leukemia (ANLL), and 2 cases of hybrid acute leukemia (HAL), According to immunophenotype of ALL, 4 subtypes were diffentiated: C-ALL, T-ALL, N-ALL, B-ALL. 3 cases of all ALL were erroneously diagnosed as having ANLL according to FAB criteria, and no single case could be diagnosed as having HAL Presented in this paper is a report of immunophenotypic findings in 65 acute leukemia, suggesting that diagnosis and classification of acute leukemia can be perfected by immunophenotypic analysis.