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阿霉素对癌症病人QT离散度的影响
引用本文:白宣英,朱步东,刘燕,于建平,张春娥. 阿霉素对癌症病人QT离散度的影响[J]. 中国医师杂志, 2003, 5(4): 498-499
作者姓名:白宣英  朱步东  刘燕  于建平  张春娥
作者单位:北京大学医学部临床肿瘤学院,北京肿瘤医院,北京,100036
摘    要:目的 探讨阿霉素对癌症病人的心电图QT,QTcd的影响。方法 对30例阿霉素化学治疗的恶性肿瘤患者用药前后的QTd及QTcd进行了分析,30例不含阿霉素的化学治疗患者作为对照。结果 阿霉素组用药后QTd及QTcd较用药前明显增大(P<0.05)。结论 阿霉素对心肌复极有一定的影响。

关 键 词:QT离散度 心脏毒性 阿霉素
文章编号:1008-1372(2003)04-0498-02
修稿时间:2002-03-18

Effects of Adriamycin on QT Dispersion in Patients With Cancer
BAI Xuan-ying,ZHU Bu-dong,LIU Yan.School of Oncolgy,Peking University and Beijing Institute for Cancer Reserch,Beijing,,China. Effects of Adriamycin on QT Dispersion in Patients With Cancer[J]. Journal of Chinese Physician, 2003, 5(4): 498-499
Authors:BAI Xuan-ying  ZHU Bu-dong  LIU Yan.School of Oncolgy  Peking University  Beijing Institute for Cancer Reserch  Beijing    China
Affiliation:BAI Xuan-ying,ZHU Bu-dong,LIU Yan.School of Oncolgy,Peking University and Beijing Institute for Cancer Reserch,Beijing,100036,China
Abstract:Objective To evaluate the effects of adriamycin on QTd and QTcd of cancer patients.Methods QTd and QTcd in 30 cancer patients before and after treated by adriamycin were measured.30 cancer patients treated without adriamycin treatment as control group.Results Value of QTd and QTcd in the patients treated by adriamycin were significantly higher than that before treated by adriamycin(P<0 05).Conclusions The findings suggest that the adriamycin could influence the repolarization of myocardium in a certain extent.
Keywords:QT dispersion  Cardiotoxicity  Adriamycin
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