| 视网膜电图和多焦视网膜电图ON/OFF反应的研究进展 |
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| 引用本文： | 张姗姗,陈长征,杨安怀. 视网膜电图和多焦视网膜电图ON/OFF反应的研究进展[J]. 眼科研究, 2009, 27(3): 253-256 |
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| 作者姓名： | 张姗姗 陈长征 杨安怀 |
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| 作者单位： | 武汉大学人民医院眼科,430070 |
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| 摘 要： | ON/OFF反应是人们从视网膜电生理反应中记录到的视网膜给光、撤光反应。它是通过不同的光感受器细胞形成不同的ON/OFF通路来完成。视网膜电图（ERG）和多焦视网膜电图（mf-ERG）ON/OFF反应的异常可明确提示ON/OFF通路及通路相关细胞的异常,在临床多种疾病,如先天性静止性夜盲,X连锁青年性视网膜病变等的诊断与治疗中有着重要意义。就ON/OFF通路（视锥ON/OFF通路,视杆ON/OFF通路,视杆慢快ON/OFF通路）和ERG、mfERGON/OFF反应的最佳记录方法、条件及在临床中的应用进行综述。
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| 关 键 词： | ON反应 OFF反应 视网膜电图 多焦视网膜电图 |
Current research on ERG and mfERG ON/OFF response |
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| Zhang Shanshan,Chen Changzheng,Yang Anhuai. Current research on ERG and mfERG ON/OFF response[J]. Chinese Ophthalmic Research, 2009, 27(3): 253-256 |
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| Authors: | Zhang Shanshan Chen Changzheng Yang Anhuai |
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| Affiliation: | Zhang Shanshan,Chen Changzheng,Yang Anhuai.(Department of Ophthalmology,Renming Hospital of Wuhan University,Wuhan 430070,China) |
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| Abstract: | ON-and OFF-response of electroretinogram（ERG） is a type of retinal response to light onset and offset.Different photoreceptor cells form different ON/OFF pathways to perform the response.The abnormality of ERG and multi-focal ERG（mfERG） ON/OFF response is helpful for definitly hinting the dysfunction of ON/OFF pathway and relative retinal cells.The record results of ON-and OFF-response has an important significance for the evaluation of clinical diagnosis and therapy of retinal disease.This article reviewed the ON/OFF pathway（cone ON/OFF pathway,rod ON/OFF pathway and rod slow-fast pathway of ON/OFF response）,the optimal recording conditions and clinical applications of ON/OFF response in ERG and mfERG. |
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| Keywords: | ON response OFF response electroretinogram mfERG |
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