牙槽骨微穿孔术加速正畸牙齿移动的研究进展

牙槽骨微穿孔术(micro-osteoperforations,MOPs)是一种创伤小、操作安全、费用低,正畸医生可以独自在椅旁完成的辅助正畸牙齿移动的干预措施。其理论基于区域加速现象(regional accelerated phenomenon,RAP),手术破坏骨组织导致术区周围骨密度降低,创伤刺激细胞调节机制使骨重建加速,达到加快正畸牙齿移动的目的。目前大部分研究验证其能够有效加速牙齿移动且可重复操作,但效果仍然存在争议,与其他加速正畸牙齿移动干预措施相比有其优缺点,本文就牙槽骨微穿孔术的提出、生物学反应、应用现状、目前可能出现的副作用作一综述,为该技术的最新发展及临床应用提供科学参考。

Research progress of micro-osteoperforation accelerated orthodontic tooth movement

Micro-osteoperforations (MOPs) are less invasive, safer, and cheaper interventions that orthodontists can perform alone at the side of chairs to assist orthodontic tooth movement. The theory is based on regional accelerated phenomenon (RAP), in which surgical destruction of bone tissue leads to a decrease in bone density around the surgical site, and the cell regulation mechanism stimulated by trauma accelerates bone reconstruction. Thus, the purpose of accelerating orthodontic tooth movement is achieved. At present, most of the research verifies that it can effectively accelerate tooth movement and be operated repeatedly, but the result remains controversial. Compared with other interventions, it has advantages and disadvantages. In this paper, the origin, biological reaction, application status and possible side effects of the micro-osteoperforations (MOPs) technique are discussed, which can provide a scientific reference for its latest development and clinical application.