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甲状腺毒性周期性麻痹患者反跳性高钾血症三例报道并文献复习
引用本文:袁海霞,贺春燕,张晶,周锋.甲状腺毒性周期性麻痹患者反跳性高钾血症三例报道并文献复习[J].中国全科医学,2022,25(15):1910-1913.
作者姓名:袁海霞  贺春燕  张晶  周锋
作者单位:1. 430081 湖北省武汉市,武汉科技大学医学院2. 430081 湖北省武汉市,武汉科技大学附属普仁医院内分泌科
基金项目:湖北省卫生健康科研基金资助项目(WJ2019H222)
摘    要:甲状腺毒性周期性麻痹(TPP)是由甲状腺毒症引起的一种内分泌急症,主要表现为周期性肌无力和低钾血症,严重威胁患者健康。血钾降低的水平与TPP患者肌无力的严重程度密切相关,补钾治疗能快速缓解患者的肌无力症状和低钾血症。但过量补钾治疗会导致TPP患者出现急性反跳性高钾血症,再次威胁患者的健康。本文报道了3例TPP患者因过量补钾治疗而导致急性反跳性高钾血症,分析引起反跳性高钾血症的危险因素,希望为TPP患者的临床治疗提供更多资料。

关 键 词:甲状腺毒性周期性麻痹  麻痹,高钾血性周期性  低钾性周期性麻痹  低钾血症  反跳性高钾血症  病例报告  
收稿时间:2021-12-15

Rebound Hyperkalemia in Patients with Thyrotoxic Periodic Paralysis: Three Cases Reports and Literature Review
Haixia YUAN,Chunyan HE,Jing ZHANG,Feng ZHOU.Rebound Hyperkalemia in Patients with Thyrotoxic Periodic Paralysis: Three Cases Reports and Literature Review[J].Chinese General Practice,2022,25(15):1910-1913.
Authors:Haixia YUAN  Chunyan HE  Jing ZHANG  Feng ZHOU
Institution:1. School of Medicine, Wuhan University of Science and Technology, Wuhan 430081, China2. Department of Endocrinology, Puren Hospital of Wuhan University of Science and Technology, Wuhan 430081, China
Abstract:Thyrotoxic periodic paralysis (TPP) is an endocrine emergency caused by thyrotoxicosis, mainly manifesting as periodic muscle weakness and hypokalemia, which seriously threatens the health of patients. The level of hypokalemia is closely related to the severity of muscle weakness in patients with TPP, and potassium supplementation can quickly alleviate the symptom of muscle weakness and hypokalemia. However, excessive potassium supplementation can lead to acute rebound hyperkalemia in patients with TPP, which also threatens the health of patients. This article reported 3 cases of TPP patients with acute rebound hyperkalemia caused by excessive potassium supplementation, and analyzed the risk factors for rebound hyperkalemia, in order to provide more information for the clinical treatment of TPP patients.
Keywords:Thyrotoxic periodic paralysis  Paralysis  hyperkalemic periodic  Hypokalemic periodic paralysis  Hypokalemia  Rebound hyperkalemia  Case reports  
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