瘢痕癌调强放射治疗一例

瘢痕癌（马乔林溃疡）多由瘢痕溃疡恶变而成，临床表现以溃疡经久不愈为主。瘢痕癌的致病因素和发病机制尚未明确，目前的诊疗方案亦尚未达成共识。该文报道1例51岁女性瘢痕癌患者，其于25年前曾有大面积的皮肤烧伤史，于入院前3个月发现右侧小腿后上方肿物，局部破溃，难以愈合，经活组织病理学检查确诊为瘢痕癌。患者接受局部调强放射治疗...

Intensity-modulated radiation therapy for scar carcinoma: a case report

Scar carcinoma (Marjolin ulcer) is mostly derived from the malignant transformation of scar ulcer with its non-healing as the main clinical manifestation. The factors and mechanisms of scar carcinoma remain elusive. Currently, no consensus has been reached on the diagnosis and treatment of scar carcinoma. In this article, the diagnosis and treatment of a 51-year-old female patient with scar carcinoma were reported. She had a history of extensive skin burns 25 years ago. A mass was found in the posterior upper part of the right calf 3 months before admission, with local rupture and difficulty of wound healing. She was diagnosed with scar carcinoma by biopsy. The patient received local intensity-modulated radiation therapy (IMRT) at 66 Gy/33F for scar carcinoma + metastatic lymph nodes and 50 Gy/25F for subclinical lesions. After local IMRT, MRI showed that the mass was smaller and the patient remained physically stable during subsequent follow-up.