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牙龈间充质干细胞递送支架载体的研究进展
引用本文:王法程,郝鹏杰,卢志山.牙龈间充质干细胞递送支架载体的研究进展[J].口腔医学,2022,42(2):170-175.
作者姓名:王法程  郝鹏杰  卢志山
作者单位:1 滨州医学院附属烟台市口腔医院牙体牙髓科,山东烟台(264008); 2 滨州医学院附属烟台市口腔医院修复科,山东烟台(264008)
基金项目:山东省医药卫生科技发展计划项目(2018WS038)
摘    要:组织工程技术通过利用支架材料、种子细胞、生长因子以达到修复或再生组织器官的目的.支架材料的作用是为种子细胞提供机械支撑并且保护细胞免受体内有害微环境的影响.因此,选择或制备适当的支架材料是组织工程中的关键一步.近年来,将支架材料和牙龈间充质干细胞(gingival mesenchymal stem cells,GMSC...

关 键 词:牙龈间充质干细胞  支架材料  天然高分子材料  人工合成材料  复合材料

Research progress of gingival mesenchymal stem cell delivery scaffolds
WANG Facheng,HAO Pengjie,LU Zhishan.Research progress of gingival mesenchymal stem cell delivery scaffolds[J].Stomatology,2022,42(2):170-175.
Authors:WANG Facheng  HAO Pengjie  LU Zhishan
Institution:Department of Endodontics, Yantai Stomatological Hospital Affiliated to Binzhou Medical College, Yantai 264008, China
Abstract:Tissue engineering technology uses scaffold materials, seed cells, and growth factors to achieve the purpose of repairing or regenerating tissues and organs. Scaffold provides mechanical support for seed cells and protects them from the harmful microenvironment in the body. Therefore, choosing or preparing appropriate scaffolds is a key step in tissue engineering. In recent years, the combined application of scaffold materials and gingival mesenchymal stem cells (GMSCs) in tissue engineering has gradually become mature. This article reviews the current research status of gingival mesenchymal stem cell delivery scaffold in tissue engineering, in order to provide ideas for the development and selection of delivery scaffolds for GMSCs tissue engineering.
Keywords:gingival mesenchymal stem cells  scaffold material  natural polymers  synthetic polymers  composite material  
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