| 一氧化氮与先天性心脏病合并肺动脉高压 |
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| 引用本文： | 冯增斌,刘苏. 一氧化氮与先天性心脏病合并肺动脉高压[J]. 心血管病学进展, 2006, 27(2): 221-223 |
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| 作者姓名： | 冯增斌 刘苏 |
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| 作者单位： | 1. 承德医学院附属医院心外科,河北,承德,067000
2. 河北医科大学第二附属医院心外科,河北,石家庄,050051 |
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| 摘 要： | 一氧化氮是一种脂溶性气体,它具有独特的理化性质和生物学活性,主要由血管内皮产生,在先天性心脏病合并肺动脉高压的发生、发展过程中起到了重要作用。吸入一氧化氮气体,可选择性扩张肺血管,降低肺动脉阻力和肺动脉压。现主要综述一氧化氮与先天性心脏病合并肺动脉高压的相互作用关系及一氧化氮在治疗上的研究进展。
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| 关 键 词： | 一氧化氮 肺动脉高压 先天性心脏病 |
| 文章编号： | 1004-3934(2006)02-0221-03 |
| 收稿时间： | 2005-09-01 |
| 修稿时间： | 2005-10-31 |
Nitric Oxide and Congenital Heart Disease Complicated Pulmonary Hypertension |
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| FENG Zeng-bin,LIU Su. Nitric Oxide and Congenital Heart Disease Complicated Pulmonary Hypertension[J]. Advances in Cardiovascular Diseases, 2006, 27(2): 221-223 |
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| Authors: | FENG Zeng-bin LIU Su |
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| Affiliation: | 1. Department of Cardiac Surgery, The Affiliated Hospital of Chengde Medical College, Chengde 067000, China ; 2. Department of Cardiac Surgery, The Second Hospital Affiliated to Hebei Medical University, Hebei 050051 , China |
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| Abstract: | Nitric oxide( NO) is liposolubility gas with distinct physioehemical property and biologic activity and it is produced chiefly by blood vessel endothelium. NO plays an important role during the development of congenital heart disease complicated pulmonary hypertension. Inhaled NO causes selective dilation of the pulmonary vasculature and decrease of pulmonary vascular resistance and pulmonary hypertension. This review provides an update on relationship between NO and congenital heart disease complicated pulmonary hypertension and research development in NO therapy. |
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| Keywords: | nitric oxide pulmonary hypertension congenital heart disease |
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