胰腺腺泡细胞癌CT、MRI诊断

目的探讨胰腺腺泡细胞癌CT、MRI表现，提高对该病的认识与影像诊断水平。方法对8例经病理证实的胰腺腺泡细胞癌cT、MRI资料回顾性分析，其中6例行CT平扫及增强检查，2例行MRI平扫及增强检查。结果男性6例，女性2例，平均年龄51岁，肿瘤位于胰头3例，体尾部3例，胰尾2例。瘤体多呈囊实性团块，最大直径约4—16cm，平均直径7cm，中心均位于胰腺外，边界多清楚：较小（〈5cm）者为实性结构为主，直径增大，囊实性比例增大。CT平扫为不均匀低密度，1例显示钙化。MRI上呈混杂信号，实性部分呈T1WI上稍低、T2WI上稍高信号，裘性部分呈T1WI上低、T2WI上高信号。CT、MR1增强扫描均见瘤内实性结构早期未见明显强化，后期呈渐进性强化，强化程度低或稍低于正常胰腺组织。袭性结构各期均无强化。8例中3例肝转移，2例显示胰胆管侵犯并扩张，脾静脉内癌栓、腹膜后淋巴结转移各1例。结论胰腺腺泡细胞癌cT、MRI表现具有一定特征性，免疫组化有助于确诊。

CT and MRI Diagnosis of Pancreatic Acinar Cell Carcinoma

Objective To investigate the imaging features of pancreatic acinar cell carcinoma. Methods CT and MRI imaging findings of 8 cases of pathologically proven acinar cell carcinomas were retrospectively analyzed, 6 of them pertbrmed plain and enhanced CT, and 2 performed plain and enhanced MRI. Results 6 male and 2 female~-~of average age 5 lyears old. 3 Masses located in the head, and 3 in the body, 2 in the tail. All masses mainly presented solid-cystic mass, the diameter ranged from 4 to 16cm, on average of 7cm, usually with sharp edge; The smaller ones presented mainly solid （〈5cm）. cystic areas, increased with the diameter. All cases showed low density on plain CT, I with calcification. All cases were mixed intense on plain MRI. and solid portions of mass showed slightly hypointense on T1WI, and iso-or slightly hyperintense on T2WI; and cystic por- tions of mass showed hypointense on T 1WI, and hyperintense on T2WI. On enhanced CT and MRI scans, solid areas showed slight enhancement in the arterial phase, then marked with the time, still less than or near to the sorrowing normal pancreatic parcnchyma. 3 cases showed liver metastasis. 2 mass invaded splenic vein, 1 case showed bile and pancreatic dilatation, retroperitoneal lymphaden metastasis. Conclusion There are some relatively specific fetures of acinar cell carcinoma on CT and MRI. The COlTect imging diagnosis and differential diagnosis is possible based on immunohistochemical staining and CT or MRI findings.