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Treatment-resistant Obsessive-compulsive Disorder in Young People: Assessment and Treatment Strategies
Authors:Georgina Krebs  & Isobel Heyman
Institution:National Clinic for Young People with OCD, South London and Maudsley NHS Foundation Trust, London SE5 8AZ, UK. Email:;
Institute of Psychiatry, King's College London, Institute of Psychiatry, London, SE5 8AF, UK
Abstract:Cognitive behaviour therapy (CBT) and selective serotonin reuptake inhibitors have both been established as effective interventions for paediatric obsessive-compulsive disorder (OCD), with CBT being the recommended first-line treatment in most cases. While the majority of young people respond well to these treatments, a significant proportion remain symptomatic. Although the research on treatment-resistant OCD remains limited, increasing empirical attention is being paid to predictors of treatment outcome in young people with OCD, and efforts are being made to identify the factors that hinder recovery. This article outlines potential barriers in treatment and highlights strategies for optimising outcome, with particular focus on cognitive behavioural techniques.
Keywords:Obsessive-compulsive disorder (OCD)  paediatric  cognitive behaviour therapy (CBT)  treatment-resistant  treatment-refractory
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