放射性龋发病因素的初步研究

为探讨放射性龋发病的相关因素和防治措施。方法，本文共收集２２例头颈部放疗患者，对其中的１０例分别于放疗前和放疗后二个月进行唾液流速和离体菌斑产酸性的检测，并比较了放疗患者与正常人唾液缓冲能力的差别。

A Study on etiologic factors or radiation caries

Objective To study the etiologic factors of radiation caries. Methods 22 patients with malignantlesions in the head and neck were included in this study. The stimulated salivary flow rate and plaque pH response in vitrowere carried out in 10 of them immediately before radiotherapy and at 2 months after its termination. The salivarybuffering capacity and flow rate of patients who had received head and neck radiotherapy were compared with those of 14healthy controls. Results The mean flow rate of the stimulated salivary secretion decreased from a preirradiation 1. 17ml/ min to 0. 34 ml/min at two months after irradiation (P< 0. 01 ). The buffering capacity of saliva in patients who hadreceived head and neck radiotherapy was lower than that of healthy people (P< 0. 01 ). The dental plaques produced moreacid in vitro after radiotherapy than before irradiation (P< 0. 01 ). Conclusion The changes in oral environment followingradiotherapy may cause radiation caries to happen.