抗菌药物应用合理性干预前后对比分析

目的考查依据抗菌药物合理用药原则指导临床用药的效果。方法选取实施干预措施前的2004年3月及干预后的2005年3月全部住院病例进行干预前后对照研究。结果干预后患者平均住院天数及抗菌药费显著降低;抗菌药物使用率显著下降;用药合理性明显提高(P<0.001)。结论采取有效可行的干预措施可缩短平均住院天数,降低抗菌药费,提高抗菌药物使用的合理性,对社会、医院和患者均有益。

Rational Use of Antibiotics: Comparative Study Before and after Intervention

OBJECTIVE To survey the effect of the intervention measures according to the guiding principle of antibiotics rational use. METHODS The data of medication of two groups of patients in Mar 2004 and Mar 2005 were collected respectively,and the condition of antibiotics use was compared. RESULTS In comparison with that in Mar 2004 the average in-hospital days and antibiotics costs in Mar 2005 were reduced remarkably;the percentage of antibiotics use was much lower;the ratio of the rational use of antibiotics increased notably(P<0.001). CONCLUSIONS The intervention measures according to the guiding principle of antibiotics rational use are effective and feasible.This principle can contribute to decreasing the average in-hospital days and antibiotics costs.It is also conducive to improving the rational use of antibiotics.The society,hospitals and patients will benefit from it.