Differential diagnosis and strategy for the treatment of anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma (ATC) is most aggressive and poor prognosis among solid neoplasmas. Unfortunately, effective treatment for ATC is not established until now. We recommend new strategy for the treatment of ATC based on new UICC staging. Stage IV is recommended the surgical treatment, and Stage IVB, IVC are recommended systemic chemotherapy like as doxorubicin and cisplatin and external radiotherapy. If tumor become decreasing by these chemoradiation, salvage surgery will be preformed for complete resection. But survival period is not longer over 20 years, so the establishment of new treatment is desired.