| 白细胞介素-21的生物学研究进展 |
| |
| 引用本文： | 李丽霞,陆羡. 白细胞介素-21的生物学研究进展[J]. 医学综述, 2006, 12(3): 166-167 |
| |
| 作者姓名： | 李丽霞 陆羡 |
| |
| 作者单位： | 广东医学院,广东,湛江,524023 |
| |
| 摘 要： | 近年来,白细胞介素2已经广泛应用到肿瘤的治疗中,但因其严重的药物毒副作用而使其未能在临床中广泛被应用。和IL2有高度同源的白细胞介素21有着和IL2相似的生物功能,特别是IL21药物的低毒性,使其在肿瘤治疗中的研究越来越受到人们的重视。本文就IL21的生物学功能,以及对IL21在肿瘤治疗中的应用前景作了综述。
|
| 关 键 词： | 白细胞介素-21 细胞因子 生物学功能 肿瘤 |
| 文章编号： | 1006-2084（2006）03-0166-02 |
| 收稿时间： | 2005-06-11 |
| 修稿时间： | 2005-11-30 |
Progress in Bioresearch of Interleukin-21 |
| |
| LI Li-xia,LU Xian. Progress in Bioresearch of Interleukin-21[J]. Medical Recapitulate, 2006, 12(3): 166-167 |
| |
| Authors: | LI Li-xia LU Xian |
| |
| Affiliation: | Guangdong Medical College, Zhanjiang 524023, China |
| |
| Abstract: | Interleukin-2 for tumors has been used widely in recent years. However, serious toxicity associated with IL-2 administration has limited its widespread use in the clinic. IL-21 which has significant homogeneity with IL-2 is similar to IL-2 in biological function. Particularly hypotoxicity of IL-21 has promoted its widely use in the tumor therapy, In this article, biological function of IL-21 and ist applied prospects for tumor therapy were reviewed. |
| |
| Keywords: | Interleukin-21 Cpokine Biological function Tumor |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
