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Bisphosphonates and atrial fibrillation: Bayesian meta-analyses of randomized controlled trials and observational studies
Authors:Anselm Mak  Mike WL Cheung  Roger Chun-Man Ho  Alicia Ai-Cia Cheak  Chak Sing Lau
Affiliation:(1) Division of Rheumatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;(2) Department of Psychology, Faculty of Arts and Social Sciences, National University of Singapore, Singapore;(3) Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;(4) Division of Rheumatology, Department of Medicine and Therapeutics, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK
Abstract:

Background  

Occurrence of atrial fibrillation (AF) amongst bisphosphonate users has been increasingly reported but results are conflicting. We performed a Bayesian meta-analysis to address the possible association between the occurrence of AF and bisphosphonate use and estimated the posterior probability of development of AF with bisphosphonate use.
Keywords:
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