鼻咽癌患者放射治疗后感音神经性耳聋的发生率及影响因素分析

目的 观察鼻咽癌患者放射治疗后感音神经性耳聋的发生情况,并探讨诱发的相关因素.方法 选取2013年6月至2014年6月收治的30例(60只耳)鼻咽癌患者,全部患者均接受放射治疗,对患者进行纯音听阈和声阻抗-导纳测试,探讨感音神经性耳聋的发生情况及诱发因素.结果 本组30例患者(60只耳)中,高频段感音神经性耳聋16只耳(26.67％),明显多于低频段感音神经性耳聋5只耳(8.33％);确诊时年龄、随访时间是影响高频段感音神经性耳聋发生的主要因素(P＜0.05).结论 鼻咽癌患者放射治疗后低频段感音神经性耳聋发生率显著低于高频段,诱发高频段感音神经性耳聋发生的因素较多,主要包括患者年龄及随访时间,临床需积极采取相关措施,尽可能降低放射治疗后感音神经性耳聋发生率,提高患者生活质量,改善预后.

The incidence of sensorineural deafness after radiotherapy in patients with nasopharyngeal carcinoma and its influencing factors

Objective To investigate the incidence of sensorineural deafness after radiotherapy in patients with nasopharyngeal carcinoma and its influencing factors.Methods 30 patients with nasopharyngeal carcinoma (NPC) (60 ears) from June 2013 to June 2014 underwent radiotherapy,pure tone audiometry and acoustic impedance-admittance test.Investigated the incidence of sensorineural deafness and induced factors.Results In 30 patients (60 ears),there were 16 ears (26.67％) with high frequency band sensorineural deafness,5 ears (8.33％) with low frequency band sensorineural deafness;age when making a definite diagnosis,followup time were influencing factors of high frequency band sensorineural deafness.Conclusions The incidence of low frequency band sensorineural deafness after radiotherapy in patients with nasopharyngeal carcinoma is lower that of high frequency band sensorineural deafness.There are many factors inducing high frequency band sensorineural deafness,including age and follow-up time.The clinical should actively take relevant measures to reduce the incidence of sensorineural deafness after radiotherapy,and improve the quality of life and prognosis.