| 尖锐湿疣病人阴毛毛囊和皮损处HPV亚型分布 |
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| 引用本文： | 王友宝,赵纯雄,韩韬.尖锐湿疣病人阴毛毛囊和皮损处HPV亚型分布[J].青岛大学医学院学报,2010,46(4):360-361. |
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| 作者姓名： | 王友宝 赵纯雄 韩韬 |
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| 作者单位： | 青岛市海慈医院泌尿外科,山东,青岛,266033 |
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| 摘 要： | 目的研究尖锐湿疣(CA)病人阴毛毛囊和皮损处人乳头状瘤病毒(HPV)阳性率及亚型分布,了解HPV亚型与临床发病的关系。方法采用PCR方法对尖锐湿疣病人皮损和阴毛毛囊中的HPV进行亚型检测。结果尖锐湿疣病人皮损处HPV阳性率为96.15%(100/104),其中75例为HPV6亚型,32例为HPV11亚型,两者混合感染11例,4例为其他亚型。尖锐湿疣病人阴毛毛囊中HPV阳性率为32.56%,其中19例为HPV6亚型,9例为HPV11亚型,两者混合感染2例,2例为其他亚型。尖锐湿疣病人皮损组织中HPV阳性率明显高于阴毛毛囊HPV阳性率(2χ=82.15,P<0.01)。尖锐湿疣病人阴毛毛囊中的HPV亚型分布与皮损中HPV亚型分布一致,两者无显著性差异(P>0.05)。结论引起男性尖锐湿疣的HPV亚型以HPV6、11亚型为主。
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| 关 键 词： | 尖锐湿疣 乳头状瘤病毒 人 皮损 |
A DISTRIBUTION OF SUBTYPE OF HUMAN PAPILLOMAVIRUS IN PUBIC HAIRS AND SKIN LESION OF PATIENT WITH CONDYLOMA ACUMINATA |
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| WANG YOU-BAO,ZHAO CHUN-XIONG,HAN TAO.A DISTRIBUTION OF SUBTYPE OF HUMAN PAPILLOMAVIRUS IN PUBIC HAIRS AND SKIN LESION OF PATIENT WITH CONDYLOMA ACUMINATA[J].Acta Academiae Medicinae Qingdao Universitatis,2010,46(4):360-361. |
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| Authors: | WANG YOU-BAO ZHAO CHUN-XIONG HAN TAO |
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| Institution: | WANG YOU-BAO,ZHAO CHUN-XIONG,HAN TAO(Department of Urology,The Affiliated Hiser Hospital of Qingdao University Medical College,Qingdao 266033,China) |
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| Abstract: | Objective To investigate the distribution of human papillomavirus(HPV) subtypes in patients with condyloma acuminata(CA) its relation with clinical morbidity. Methods Specimens from folliculus pili of pubic hairs and skin lesions of patients with CA were detected and checked for HPV subtypes. Results The positive HPV in impaired skin was 96.15%(100/104),in which,75 was classified as subtype HPV6,and 32 as HPV11,combined infection of the above two subtypes was 11 cases,and four cases were other subtypes.The ... |
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| Keywords: | condylomata acuminata papillomavirus human skin lesion |
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