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前列腺癌与前列腺增生的MRI和MRS特点分析
引用本文:高志国,龚良赓,肖新兰,尹建华.前列腺癌与前列腺增生的MRI和MRS特点分析[J].江西医学院学报,2008,48(6):56-59.
作者姓名:高志国  龚良赓  肖新兰  尹建华
作者单位:南昌大学研究生院医学部;南昌大学第二附属医院磁共振室;
基金项目:江西省卫生厅科技计划资助  
摘    要:目的分析前列腺癌(PCa)与前列腺增生(BPH)的MRI和MRS表现,探讨两者对PCa和BPH的鉴别诊断。方法回顾性分析经病理和随访证实的31例PCa和41例BPH患者的MRI、MRS表现,其中26例行MRS检查。MRI观察前列腺的大小、形态、病变位置、信号特点及肿瘤侵犯范围;MRS观察枸橼酸盐(Cit)、胆碱复合物(Cho)和肌酸(Cre)的波峰和化学位移,并计算(Cho+Cre)/Cit(CC/C)比值。结果①MRI表现:PCa主要位于周围带(29/31,94%),T2WI均表现为结节状或片状低信号;BPH主要位于中央腺体(39/41,95%),T2WI表现为弥漫性混杂信号(18例)、圆形或结节状的高信号(17例)和低信号(6例)。②MRS表现:BPH的Cit峰升高,CC/C比值(0.79±0.25)下降;PCa的Cit峰下降,Cho峰升高,CC/C比值(2.34土1.21)升高,与BPH比较有显著差异(t=4.327,P〈0.001)。结论MRI能很好地显示BPH和PCa的位置和信号特点,MRS能提供前列腺良、恶性组织的代谢信息,两者联合诊断有助于提高PCa和BPH的鉴别水平。

关 键 词:前列腺增生  前列腺癌  磁共振成像  磁共振波谱

Analysis of the Characteristics of Prostate Carcinoma Benign Prostate Hyperplasia and in MRI and MRS
GAO Zhi-guoa,Gong Liang-gengb,XIAO Xin-lanb,YIN Jian-huab.Analysis of the Characteristics of Prostate Carcinoma Benign Prostate Hyperplasia and in MRI and MRS[J].Acta Academiae Medicinae Jiangxi,2008,48(6):56-59.
Authors:GAO Zhi-guoa  Gong Liang-gengb  XIAO Xin-lanb  YIN Jian-huab
Institution:a.2006 Grade of Medical Department of Graduate School;b.Department of Radiology;the Second Affiliated Hospital;Nanchang University;Nanchang 330006;China
Abstract:Objective To analyze the MRI and MR spectroscopy(MRS) appearances of benign prostate carcinoma(PCa) and prostate hyperplasia(BPH),and the value of MRI and MRS in the differential diagnosis of PCa and BPH.MethodsThe clinical datas and MRI,MRS appearances in 31 patients with PCa and 41 patients with BPH proved by pathology were retrospectively analyzed and follow-up,and 26 cases underwent MRS scan.MRI observed the size of prostate,the location of the lesion,the signal features and the extension of the tumors....
Keywords:benign prostate hyperplasia  prostate carcinoma  MR imaging  MR spectroscopy  
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