| 亚砷酸对急性早幼粒细胞白血病患者红细胞系及巨核细胞系的影响 |
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| 引用本文： | 胡宏,魏锦,陈静,王勇.亚砷酸对急性早幼粒细胞白血病患者红细胞系及巨核细胞系的影响[J].四川医学,2001,22(8):713-714. |
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| 作者姓名： | 胡宏 魏锦 陈静 王勇 |
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| 作者单位： | 川北医学院附属医院 |
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| 摘 要： | 目的 探讨亚砷酸对急性早幼粒细胞白血病（APL）患者红细胞系及巨核细胞系的影响。方法 11例初治的APL患者经亚砷酸治疗后观察血象及髓髓象的情况。结果 亚砷酸治疗2周内血红蛋白及血小板基本无变化，随着治疗时间延长红细胞系3周后，巨核细胞系4周后则逐渐恢复造血。结论 亚砷酸对急性早幼粒细胞白血病患者红细胞系及巨核细胞系基本无抑制。
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| 关 键 词： | 急性白血病 早幼粒细胞白血病 巨核细胞系 亚砷酸 诱导分化疗法 |
| 文章编号： | 1004-0501(2001)08-0713-02 |
| 修稿时间： | 2001年6月5日 |
The effect of arsenons acid on the erythrons and megakaryocytes with acute promyelocytic leukemia. |
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| Hu Hong,Wei Jin,Chen Jing,et al..The effect of arsenons acid on the erythrons and megakaryocytes with acute promyelocytic leukemia.[J].Sichuan Medical Journal,2001,22(8):713-714. |
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| Authors: | Hu Hong Wei Jin Chen Jing |
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| Institution: | Hu Hong,Wei Jin,Chen Jing,et al.Affiliated Hospital of North Sichuan College,Nanchong,Sichua n,637000 |
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| Abstract: | Objective To investig ate the effects of arsenons acid(AA) on erythrons and megakaryocytes in acute pr omyelocytic leukemia(APL).Methods Analysis on the peripheral and bone ma rrow aspiration smears of 11 patients wi th APL after using AA in the initial tre atment.Results Hemoglobin,3 week s later and platelets,4 weeks later,grad ually recovered to normal after the use of AA in the treatment.Conclusion The use of arsenons acid in the treatm ent of acute promyelocytic leukemia woul d not,on the whole, result in depression of erythrons and megakaryocytes. |
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| Keywords: | Acute promyelicytic l eukemia Erythron Megakaryocyte Arsenons acid Induction of differentiation therap y |
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