非侵入性指标预测中重度食管静脉曲张的临床研究

目的探讨血小板计数（PC）、脾脏指数（SI）、血小板计数／脾脏指数（PC／SI）、门静脉宽度（PV）、脾静脉宽度（SV）、门静脉宽度／脾静脉宽度（PV／SV）在预测中重度食管静脉曲张（EV）中的意义。方法测量196例肝硬化患者的PV、SV、脾脏长径（SL）及厚度（ST）（SI=SL×ST）、PC，应用ROC曲线下面积（AUC）的值评价上述非侵入性指标预测中重度EV的准确性。结果PC／S1、PC、PV／SV的AUC分别为0．870、0．781、0．655；PV、SV、SI的AUC不足0．5。PC／SI≤0．97时，预测中重度EV的敏感度为89．4％，特异度为70．6％。结论PC／SI是预测中重度EV较理想的非侵入性指标，当PC／SI〈0．97时，判断中重度EV存在的敏感度、特异度最高。

Non-invasive prediction of presence of medium or large esophageal varices in cirrhosis

Objective To evaluate the non-invasive predictive indexas of presence of medium or large esophageal varices in cirrhosis, such as platelet count （PC） , splenic index （SI） , PC/SI ,portal vein diameter （PV） , splenic vein diameter （ SV ） and PV/SV. Methods The retrospective analysis was performed in 196 patients with hepatic cirrhosis. The PV ,SV ,splenic length （SL） ,splenic thickness （ST） （ SI = SL × ST）, and PC were recorded. The accuracy of all the non-invasive parameters in predicting the presence of medium or large varices was evaluated by the area under the receiver operating characteristic （ ROC ） curves （AUC）. Results The AUC value generated by the ROC curves for PC/ SI was 0. 870,higher than the others. Conclusions It suggested that PC/SI is an ideal non-invasive predictive indexes of the presence of the medium or large varices. When PC/SI 〈0. 97 ,the sensitivity （89. 4% ） and specificity （70. 6% ） are highest in predicting medium or large varices.