| 鹿茸提取物体外抗氧化作用 |
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| 引用本文： | 陈晓光,金淑莉,邸琳,刘新宇,宋海鹏. 鹿茸提取物体外抗氧化作用[J]. 中药材, 2003, 26(10): 733-734 |
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| 作者姓名： | 陈晓光 金淑莉 邸琳 刘新宇 宋海鹏 |
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| 作者单位： | 1. 吉林省中医中药研究院,长春,130021
2. 长春公交医院,长春,130021 |
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| 摘 要： | 目的：研究鹿茸提取物的体外抗氧化作用。方法：测定鹿茸提取物对NADPH-维生素c和Fe^2 -半胱氨酸系统诱发的微粒体脂质过氧化反应(MDA形成)的影响，及对黄嘌呤-黄嘌呤氧化酶系统超氧阴离子自由基(O2^-.)产生(还原型细胞色素C形成)的影响。结果：鹿茸提取物在体外能明显抑制NADPH-维生素C和Fe^2 -半胱氨酸系统诱发的大鼠脑、肝、肾微粒体脂质过氧化反应(MDA形成)，及黄嘌呤黄嘌呤氧化酶系统O2^-.的产生(还原型细胞色素C形成)。结论：鹿茸提取物具有抗氧化作用。
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| 关 键 词： | 鹿茸提取物 抗氧化作用 中药 脂质过氧化 丙二醛 超氧阴离子自由基 小鼠 |
| 修稿时间： | 2003-03-20 |
Anti-lipid Peroxidaton of the Water Extract from Cornu Cervi Pantotrichum |
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| Chen Xiaoguang ,Jin Shuli ,Di Lin ,Liu Xinyu ,Song Haipeng. Anti-lipid Peroxidaton of the Water Extract from Cornu Cervi Pantotrichum[J]. Journal of Chinese medicinal materials, 2003, 26(10): 733-734 |
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| Authors: | Chen Xiaoguang Jin Shuli Di Lin Liu Xinyu Song Haipeng |
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| Affiliation: | Academy of Traditional Chinese Medicine and Materia Medica of Jilin Province, Changchun 130021. |
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| Abstract: | Objective: To investigate the anti lipid peroxidation of the water extract from Cornu Cervi Pantotrichum (WECCP) in vitro Mehtods: The lipid peroxidation (malondialdehyde formation) in microsomes of rat brain, liver and kidney induced by NADPH Vit C and cyctein Fe 2+ , and the superoxide anion radical production(reduced cytochrome c formation) in xanthine xanthine oxidase system in vitro were evaluated Results: The lipid peroxidation(MDA fromation) in microsomes of rat brain, liver and kidney induced by NADPH Vit C and cyctein Fe 2+ , O 2 production(reduced cytochrome c formation) in xanthine xanthine oxidase system were significantly inhibited by WECCP Conclusion: WECCP exhibits an antioxidant activity |
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| Keywords: | Cornu Cervi Pantotrichum Lipid peroxidation Malondialdehyde Superoxide anion radical |
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