| MOSAICISM CONFINED TO PLACENTA IN PREGNANCIES WITH ADVERSE OUTCOME |
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| 引用本文： | 向阳 KarinSundberg BjarneBeck 孙念怙. MOSAICISM CONFINED TO PLACENTA IN PREGNANCIES WITH ADVERSE OUTCOME[J]. 中国医学科学杂志(英文版), 1995, 10(1): 45-49 |
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| 作者姓名： | 向阳 KarinSundberg BjarneBeck 孙念怙 |
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| 作者单位： | [1]DepartmentofObstetricsandGynecology,PekingUnionMedicalCollegeHospital,Beijing100730 [2]DepartmentofObstetricsandGynecology,UniversityHospi-talofCopenhagen,Denmark [3]DepartmentofObstetricsandGynecology,PekingUnionMedicalCollegeHospital,Beijing100730 |
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| 摘 要： | Chorionic villi and feral tissues from 50 pathological human conceptions ar gesrarional weeks 9-40 were cultured and cytogenetically analyzed to explore the existence of chromosomal mosaicism confined to the extraembryonic tissues and to clarify the relationship between confined placental mosaicism and adverse outcome of pregnancy. Chorionic villi and fetal rlssues from 12 second trimester gesrations terminated for social reasons served as a control group. In two pathological gestations, true mosaicism was found exclusively in chorionic cells and could not be confirmed in cells derived from the fetal tissues, One of these was severely growth retarded, Concordant results were obtained in all other cases,
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| 关 键 词： | 胎盘镶嵌 妊娠结局 绒毛膜组织 临床研究 |
MOSAICISM CONFINED TO PLACENTA IN PREGNANCIES WITH ADVERSE OUTCOME |
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| Xiang Yang,Karin Sundberg,Bjarne Beck and Sun Nianhu. MOSAICISM CONFINED TO PLACENTA IN PREGNANCIES WITH ADVERSE OUTCOME[J]. Chinese medical sciences journal, 1995, 10(1): 45-49 |
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| Authors: | Xiang Yang Karin Sundberg Bjarne Beck Sun Nianhu |
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| Abstract: | Chorionic villi and fetal tissues from 50 pathological human conceptions at gestational weeks 9-40 were cultured and cytogenetically analyzed to explore the existence of chromosomal mosaicism confined to the extraembryonic tissues and to clarify the relationship between confined placental mosaicism and adverse outcome of pregnancy. Chorionic villi and fetal tissues from 12 second trimester gestations terminated for social reasons served as a control group. In two pathological gestations, true mosaicism was found exclusively in chorionic cells and could not be confirmed in cells derived from the fetal tissues. One of these was severely growth retarded. Concordant results were obtained in all other cases. |
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| Keywords: | Confined placental mosaicism fetal loss chorionic villi |
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