热毒宁、单磷酸阿糖腺苷联合治疗手足口病的疗效分析

目的观察热毒宁联合单磷酸阿糖腺苷治疗小儿手足口病临床疗效。方法将145例手足口病患儿随机分为治疗组73例，对照组72例，对照组予以单磷酸阿糖腺苷10mg／（kg·d），治疗组在对照组治疗的基础上给予热毒宁0．5～lmL／（kg·d），1次／天，疗程7d，对临床有效率及体征的变化进行分析。结果治疗组疗效好于对照组，有效率（P〈0．01）及临床症状改善（P〈0．01）均有显著性差异。结论热毒宁联合单磷酸阿糖腺苷治疗手足口病可有效改善临床症状，减少并发症发生，缩短病程。

To Analyse the Curative Effect of Reduning Combined with Adenine Arabinoside Monophosphate on Children with Hand-foot-and-mouth Disease

Objective To analyse the curative effect of Reduning combined with adenine arabinoside monophosphate on children with Hand-foot-and- mouth disease（HFMD）.Methods 145 cases patients with HFMD were divided into two groups randomly. The treatment group（73case） were treated with adenine arabinoside monophosphate 10mg/（kg.d）] and contral group（72case） were treated with Reduning 0.5-1mL/（kg·d）],seven days for one period of treatment. Results The total effective rate was 95.9% in the treatment group and 83.3%in the contral group （P〈0.01）; Clinical symptom improvement rate were significantily higher than those of the contral group （P〈0.01）. Conclusions Reduning combined with adenine arabinoside monophosphate on children with HFMD can improve clinical symptoms, reduce the incidence of complication and shorten the course of disease.