| 老年慢性阻塞性肺疾病患者血清IL-8水平变化的临床观察 |
| |
| 引用本文： | 玉建勋,邝晓聪,吴隐鑫,温冠媚. 老年慢性阻塞性肺疾病患者血清IL-8水平变化的临床观察[J]. 广西医学, 2006, 28(7): 995-997 |
| |
| 作者姓名： | 玉建勋 邝晓聪 吴隐鑫 温冠媚 |
| |
| 作者单位： | 广西南宁市红十字会医院内科,南宁,530012;广西医科大学病理生理教研室 |
| |
| 基金项目： | 广西医疗卫生自筹经费课题 |
| |
| 摘 要： | 目的观察急性发作期以及缓解期的老年慢性阻塞性肺疾病(COPD)患者血清IL-8水平变化.方法选择急性发作期以及缓解期的老年COPD患者23例,采用竞争放射免疫法检测血清IL-8水平变化,并进行急性发作期血清IL-8水平与白细胞计数、分类的相关性分析.结果在老年COPD患者急性发作期血清IL-8显著高于缓解期和正常对照组(P＜0.05),但与患者急性发作期白细胞中淋巴细胞、粒细胞计数、分类的无明显相关性.结论血清IL-8参与老年COPD的气道炎症的不同过程.
|
| 关 键 词： | 慢性阻塞性肺疾病 炎性细胞趋化因子 竞争放射免疫法 |
| 收稿时间： | 2006-02-21 |
| 修稿时间： | 2006-05-16 |
Investigation into the serum level of interleukin-8 in the old age patients with COPD |
| |
| YU Jian-xun,KUANG Xiao-cong,WU Yin-xin,WEN guan-mei. Investigation into the serum level of interleukin-8 in the old age patients with COPD[J]. Guangxi Medical Journal, 2006, 28(7): 995-997 |
| |
| Authors: | YU Jian-xun KUANG Xiao-cong WU Yin-xin WEN guan-mei |
| |
| Affiliation: | Department of Internal Medicine, Sanning Red Cross Hospital Sanning, 530012 Department of eathyophysiology of Guangxi Medical University |
| |
| Abstract: | Objective To investigate the surem levels of IL-8 the defferent stages of old age patient with COPD.Methods 23 old age patients with COPD and 15 healthy controls were enrolled in the clinical research.IL-8 was detected by RIA.Then the relationship between IL-8 and differential white blood cell count were analyzed by statistic methods.Results:At acute stage of the old age patients with COPD,the level of IL-8 was significantly higher than the level of IL-8 at recover stage and control groups.There were no significant correlations between the serum level of IL-8 and differential white blood cell count at acute stage.Conclusion IL-8 plays important roles in the airway inflammation of the old age patients with COPD. |
| |
| Keywords: | Chronic Obstructive Pulmonary disease Interleukin-8 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
