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高血压病血瘀证患者血液学指标判别分析
引用本文:姚魁武,杨戈,王阶. 高血压病血瘀证患者血液学指标判别分析[J]. 世界科学技术, 2006, 8(5): 30-32,42
作者姓名:姚魁武  杨戈  王阶
作者单位:[1]中国中医科学院西苑医院,北京100091 [2]中国中医科学院广安门医院,北京100053
基金项目:国家重点基础研究发展计划(973计划);国家自然科学基金
摘    要:目的:探讨高血压病血瘀证患者血液学指标中内皮素功能、血脂、纤溶系统的变化对于该证的相关性和贡献度。方法:对161例高血压病人的纤溶酶原激活物、一氧化氮、内皮素、高密度脂蛋白、总胆固醇及甘油三酯等6因素指标进行判别分析,并进行回顾性检验和前瞻性检验。结果:得出第一典则判别函数、血瘀型和非血瘀型的判别函数,并且进行了回顾性检验和前瞻性检验,两者的判断总正确率分别为86,8%和80.08%。在6因素中,高密度脂蛋白的地位尤其突出。结论:该判别函数式判别阳性结果较高,具有一定的应用价值,高密度脂蛋白在高血压病人的发生发展过程中地位比较重要。

关 键 词:血瘀证  高血压病  判别分析
收稿时间:2006-03-13
修稿时间:2006-03-132006-10-18

Discriminant Analysis of Hematological Indicators for Hypertension Based Blood Stasis Syndrome
Yao Kuiwu,Yang Ge,Wang Jie. Discriminant Analysis of Hematological Indicators for Hypertension Based Blood Stasis Syndrome[J]. World Science and Technology(Modernization of Traditional Chinese Medicine), 2006, 8(5): 30-32,42
Authors:Yao Kuiwu  Yang Ge  Wang Jie
Abstract:The purpose of this study is to look into the relevance and contribution of endothelin, lipoprotein, and fibrinolysis to the blood stasis syndrome (BSS) in hypertension patients. In the study, a discriminant analysis was made to see the effects of 6 selected indicators on 161 hypertension patients. A retrospective and prospective analysis was also made for the same purpose. Derived from the study are the canonical discriminant function 1 and the discriminant function of BSS and non-BSS, with an accuracy of 86.8% and 80.08% respectively for the retrospective and prospective analysis. High-density lipoprotein (HDL) is on the top of the 6 hematological indicators. It is concluded that the discriminant functions derived from the study, having a relatively high positive readout, are of possible application values. The variation of HDL is important for interpreting the development of hypertension disease.
Keywords:blood stasis syndrome   hypertension disease   discriminant analysis
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