22例嗜酸细胞增多性脑膜脑炎患者临床分析

目的 阐明了广州管圆线虫所致嗜酸细胞增多性脑膜脑炎的临床特点，方法 分析２２例嗜酸细胞增多性脑膜脑炎患者的临床表现，实验室和流行病学资料，结果 临床特点为（１）以疼痛为主诉，头痛和脊神经根刺激症状明显；（２）头痛剧烈而脑膜刺激征缺乏；（３）半数以上病人伴有嗜酸粒细胞性肺炎；（４）周围血像，脑脊液中嗜酸性粒细胞增高，（５０预后好，属自限性疾病；结论，广州管圆线虫是嗜酸细胞增多性剧脑膜脑炎最主要的病因

The clinical feature analysis on 22 patients with eosinophilic meningaencephalitis

Objective To illustrate the clinical features of eosinophilic meningoencephalitis caused by Angiostrongylus cantonensis. Methods The clinical findings,the laboratory data and the epidemiological information were analysed in 22 patients with eosinophilic meningoencephalitis. Results The clinical features as follows:1)Pain was a chief complaint. Headache and irritation of the spinal nerve roots were sharp. 2)They had severe headache with mild meningeal signs 3) Over half of the patients had eosinophilic pneumonia at the same time. 4) Eosiphilia in the peripheral blood and eosinophilic pleocytosis were prominent.5) The prognosis was better and the course of the disease might be self limited. Conclusion Angiostrongylus cantonensis is one of the most common causes leading to eosinophilic meningoencephalitis.