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布-加综合征介入治疗并发股动脉假性动脉瘤的治疗探讨
引用本文:邵永,魏宁,徐浩,祖茂衡,王兴田,冯栋栋.布-加综合征介入治疗并发股动脉假性动脉瘤的治疗探讨[J].徐州医学院学报,2013(11):725-728.
作者姓名:邵永  魏宁  徐浩  祖茂衡  王兴田  冯栋栋
作者单位:[1]徐州医学院附属医院普通外科,江苏徐州221002 [2]徐州医学院附属医院介入放射科,江苏徐州221002 [3]徐州医学院附属医院超声科,江苏徐州221002
基金项目:江苏省"科教兴卫工程"--布-加综合征基础及介入治疗研究创新团队(LJ201143)
摘    要:目的 探讨布-加综合征介入术后并发股动脉假性动脉瘤的原因和治疗措施.方法 回顾分析8例下腔静脉阻塞型布-加综合征患者在介入术中或术后1~2天股静脉(均为右侧)穿刺处出现搏动性肿块,经彩色多普勒超声明确诊断为股动脉假性动脉瘤,显示瘤体大小(长径×短径)为1.2 cm×0.6 cm~10.4 cm×4.8 cm.5例接受超声引导下加压治疗,3例接受超声引导下瘤内凝血酶注射治疗.结果 5例接受超声定位下加压治疗者,时间持续20~40 min,瘤颈闭合和瘤体内血栓形成;3例接受超声引导下瘤内凝血酶注射术(瘤体大小为2.5 cm×1.6 cm、3.8 cm×2.1 cm和10.4 cm×4.8 cm),其中1例1次成功封闭瘤腔,2例行2次凝血酶注射并持续压迫瘤腔直至愈合,总剂量分别为200 U、300 U和800 U,术后未发生远端动脉栓塞、过敏等并发症.所有患者随访1~6个月无复发.结论 布-加综合征介入治疗并发的股动脉假性动脉瘤,采用超声引导下加压、瘤体内注射凝血酶等治疗取得了良好的临床疗效.

关 键 词:布-加综合征  股静脉  动脉瘤  假性  凝血酶

Clinical analysis of treatment of femoral pseudoaneurysm following interventional therapy for Budd-Chiari syndrome
SHAO Yong,WEI Ning,.,XU Hao,ZU Maoheng,WANG Xingtian,FENG Dongdong.Clinical analysis of treatment of femoral pseudoaneurysm following interventional therapy for Budd-Chiari syndrome[J].Acta Academiae Medicinae Xuzhou,2013(11):725-728.
Authors:SHAO Yong  WEI Ning    XU Hao  ZU Maoheng  WANG Xingtian  FENG Dongdong
Institution:3 ( 1. Department of General Surgery, the Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu 221002, China; 2. Department of Interventional Radiology, the Affiliated Hospital of Xuzhou Medical College; 3. Department of Ultrasound,the Affiliated Hospital of Xuzhou Medical College)
Abstract:Objective To investigate the reason and treatment of femoral pseudoaneurysm following interventional therapy for Budd - Chiari syndrome ( BCS ). Methods A retrospective review was conducted on 8 patients presented with BCS caused by obstruction of the inferior vena cava during January 1990 to August 2012, who had been found a pul- satile mass at the area of femoral venipuncture point ( all on the right side) during or 1 to 2 days after interventional thera- py for BCS. The masses were all confirmed to be femoral pseudoaneurysm on the affected side by color Doppler flow image (CDFI) , with its body size ( major diameter x minor diameter) of 1.2 cm x 0.6 cm to 10.4 cmx 4.8 cm. 5 cases re- ceived ultrasound- guided compression repair (UGCR) and 3 cases received ultrasound -guided thrombin injection (UGTI, 500 U thrombin dissolved in 10 ml normal saline). Results The neck of the aneurysm was sealed off and thrombosis formed in its body in 5 cases after UGCR for 20 - 40 min. Among 3 cases ( the pseudoaneurysm body were 2.5 em x 1.6 em, 3.8 cm x 2.1 em and 10.4 em x4.8 cm respectively) who received UGTI, the cavity of the aneurysm was sealed off successfully in 1 case after UGTI, second UGTI was performed in 2 cases and the cavity of the aneurysm was sealed off. The total dose of thrombin was 200 U, 300 U and 800U, respectively. No complications such as arterial embolism at the distal end of the leg and allergy happened. All of the 8 cases were followed up at 1 to 6 months with no relapse. Conclusion UGCR and UGTI are easy and effective treatment for femoral pseudoaneurysm following interven- tional therapy for BCS.
Keywords:Budd - Chiari syndrome  femoral vein  pseudoaneurysm  thrombin
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