帕歌斯治疗膝关节骨关节炎、退行性脊柱炎的初步观察

目的 :验证帕歌斯治疗膝关节骨关节炎、退行性脊柱炎的临床疗效。方法 :随机分为治疗组和对照组各30例。治疗组应用帕歌斯 ,对照组应用枢力达。1个月后观察膝关节骨关节炎及退行性脊柱炎的主要症状和疼痛、关节功能、肿胀情况。结果 :膝关节骨关节炎治疗组总有效率88 9 % ,对照组为82 4 % ;退行性脊柱炎治疗组总有效率83 3 % ,对照组为81 8 %。经统计学处理 ,两组总有效率均无显著性差异 (P>0.05) ,疗效相似。结论 :帕歌斯与非甾体类药物枢力达一样都具有抗炎、消肿、止痛、改善关节功能的疗效 ,帕歌斯无明显副反应 ,而非甾体类药物枢力达有一定比例的胃肠道副反应

Preliminary Observation on Pagosid in Treatment of Osteoarthritis of Knee Joint and Retrograde Spondylitis

AIM:To verify the therapeutic effect of pagosid in treating osteoarthritis of knee joint and retrograde spondylitis METHODS:60 patients were randomly divided into treatment group(pagosid)and control group(zulida) The clinical manifestations of osteoarthritis and spondylitis,including pain,joint dysfunction and swelling,were observed one month after treatment RESULTS:The total effective rates for osteoarthritis were 88 9% in treatment group and 82 4% in control group and those for spondylitis were 83 3% in treatment group and 81 8% in control group There were no statistical differences between two groups(P>0 05) CONCLUSION:Both pagosid and zulida have the therapeutic effects on inflammation,pain,swelling and dysfunction of joint,and pagosid does not induce adverse reactions,while zulida could result in considerable gastroenteric tract side reactions