| 影响头孢克罗缓释片释药因素的研究 |
| |
| 引用本文： | 尹莉芳,李欣.影响头孢克罗缓释片释药因素的研究[J].中国药科大学学报,1999,30(6):19-21. |
| |
| 作者姓名： | 尹莉芳 李欣 |
| |
| 作者单位： | 中国药科大学药剂学教研室!南京210009 |
| |
| 摘 要： | 以 HPMC为缓释材料 ,采用湿法制粒制备缓释片 ,用体外释放度试验研究了缓释片的释药机理及影响因素。结果表明 ,缓释片的释放符合 Higuchi方程 ,HPMC的粘度、用量、丙烯酸树脂 号的用量、硬度对其释药速率均有明显影响
|
| 关 键 词： | 头孢克罗 缓释片 释药速率 HPMC |
The Factors Influencing on Cefaclor Release From Sustained Release Tablets |
| |
| Yin Lifang,Tu Xide,Li Xin\.The Factors Influencing on Cefaclor Release From Sustained Release Tablets[J].Journal of China Pharmaceutical University,1999,30(6):19-21. |
| |
| Authors: | Yin Lifang Tu Xide Li Xin\ |
| |
| Institution: | Yin Lifang,Tu Xide,Li Xin\ 1 Department of Pharmaceutics,China Pharmaceutical University,Nanjing 210009\, |
| |
| Abstract: | Cefaclor sustained-release tablets were prepared with wet methods, the mechanism and the influencing factors on drug release were studied through the releasing tests. The results showed that the drug releasing rate from the tablets followed Higuchi equation and the effects of HPMC viscosity, content, Eudragit L100 content, pressure on cefaclor release were significant. |
| |
| Keywords: | Cefaclor Sustained release tablet Release rate Hydroxypropyl methylcellulose |
| 本文献已被 CNKI 维普 等数据库收录！ |
| 点击此处可从《中国药科大学学报》浏览原始摘要信息 |
| 点击此处可从《中国药科大学学报》下载免费的PDF全文 |
|
