精神分裂症临床类型变异的自身对比

目的 了解复发性精神分裂症临床类型的稳定性，并探讨影响亚型稳定的相关因素。方法 对830例复发性精神分裂症患者，按CCMD－2－R由三级医师对各次住院进行重新确定亚型，然后对每例患者的各次住院亚型的变化进行自身对比和Logistic回归分析。结果 亚型变异率为34．7％，未定型和青春型的变异率较高。不规则治疗、阳性症状多、反复多次住院、阳性家庭史、初发年龄小、未婚和锥体外系副反应较重为亚型改变的主要影响因素。结论 受多种因素影响，精神分裂症部分亚型不稳定。

A self-comparative variances of clinical types in schizophrenia

Objectives: To understand the stability of the clinical types of schizophrenia and the factors related to the subtype stability. Method : The subtypes of 830 inpatients with schizophrenia were re-determined according to CCMD-2-R. then. the variances of subtypes among hospitalizations were analyzed with self-comparison and Logistic regression . Results: The subtype variant rate was 34. 7%. There were higher variant rates in undifferentiated and hebephrenic types. The major influence factors of subtypes instability were irregular treatment, more positive symptoms, more hospitalizations, history of psychosis, onset at younger age, unmarried and severer EPS side-effect. Conclusion: Some subtypes of schizophrenia were instable under the influences of many factors.