| 学习和记忆对大鼠背海马结构内C—FOS表达的影响 |
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| 引用本文： | 张玉秋 梅俊. 学习和记忆对大鼠背海马结构内C—FOS表达的影响[J]. 中国神经科学杂志, 2000, 16(2): 138-142 |
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| 作者姓名： | 张玉秋 梅俊 |
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| 作者单位： | 上海医科大学医学神经生物学国家重点实验室!上海200032(张玉秋),西安医科大学生理学教研室!陕西西安710061(梅俊) |
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| 摘 要： | 采用避暗回避反应实验和免疫组织化学相结合的方法,选用五个时间点对Ｃ－ＦＯＳ在大鼠背海马结构的表达进行了观察。结果表明,训练后１５ｍｉｎ,大鼠背海马各区ＦＯＳ样免疫阳性神经元数量开始增加,训练后１小时峰值,记忆唤醒也可诱导大鼠背海马各区Ｃ－ＦＯＳ的表达,提示学习和记忆过程与背海马内Ｃ－ＦＯＳ的表达密切相关。
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| 关 键 词： | C－FOS 学习 记忆 背海马结构 大鼠 |
The effect of learning and memory on expression of C-FOS in rat dorsal hippocampal formation |
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| ZHANG Yu qiu ,MEI Jun. The effect of learning and memory on expression of C-FOS in rat dorsal hippocampal formation[J]. Neuroscience Bulletin, 2000, 16(2): 138-142 |
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| Authors: | ZHANG Yu qiu MEI Jun |
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| Affiliation: | ZHANG Yu qiu 1,MEI Jun 2 |
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| Abstract: | With dark avoidance task and immunocytochemical method,the present study investigated the C FOS expression in dorsal hippocampal formation of rats at five different time points(15 min,1,2,6 and 24 h after training).The results showed that the number of FOS like immunoreactive neurons in dorsal hippocampal formation began to increase at 15 min,and the peak occurred at 1 hour after training,The C FOS expression was also activated by memory arouse.These results indicated that the C FOS expression involved in learning and memory processes. [ |
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| Keywords: | dark avoidance task C-FOS learning and memory dorsal hippocampal formation |
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