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普罗布考与两种降血脂药的疗效比较
引用本文:许树旭,王文信,方树青. 普罗布考与两种降血脂药的疗效比较[J]. 解放军药学学报, 1999, 15(4): 21-22,F003
作者姓名:许树旭  王文信  方树青
作者单位:中国人民解放军第266医院,承德,067000
基金项目:河北省经贸委重点科研项目
摘    要:目的:观察比较新药普罗布考片与其它两种降血脂药的降脂作用。方法:197例高脂血症患者随机分组,分别口服藻酸双酯钠片(100mg.tid)、非诺贝特片(100mg.tid)和普罗布考片(250mg.tid)。于第4周、第8周抽空腹血测定血脂值。结果:服药8周后,普罗布考组降血清总胆周醇(TC)总有效率84.4%;藻酸双酯钠组和非诺贝特组分别为75.5%和75.9%。服普罗布考期间,仅发现少而轻的不良反应。结论:普罗布考片为安全显效的降血脂药。

关 键 词:普罗布考  非诺贝特  藻酸双脂钠片

COMPARISON OF EFFECTS ON PROBUCOL AND THE TWO OTHER LIPIDEMIA-LOWERING DRUGS
Xu Shuxu,Wang Wenxin,Fang Shuqing. COMPARISON OF EFFECTS ON PROBUCOL AND THE TWO OTHER LIPIDEMIA-LOWERING DRUGS[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 1999, 15(4): 21-22,F003
Authors:Xu Shuxu  Wang Wenxin  Fang Shuqing
Abstract:AIM To compare the effects of Probucol with polysaccharide sodium(p.s.s) and fenofibrate.METHODS The blood lipid was derermined in 197 patients with hyperlipidemia treated with probucol,p.s.s and fenofibrate after 4 and 8 weeks respectively.RESULTS The total effectve rate of probucol was 84.4%,while the effective rate of two other agent was 75.5 and 75.9% respectively.CONCLUSION Probucol tablets are safe and effective in lowering bloodlipid.
Keywords:Probucol  polysaccharide sodium  fenofibrate  comparison
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