| 肺结核病人外周血淋巴细胞化学发光改变 |
| |
| 引用本文： | 周向东,杨肇亨,洪新,李天星.肺结核病人外周血淋巴细胞化学发光改变[J].中国防痨通讯,1996(2). |
| |
| 作者姓名： | 周向东 杨肇亨 洪新 李天星 |
| |
| 作者单位： | 第三军医大学大坪医院 |
| |
| 摘 要： | 采用液闪单光子辐射法检测肺结核病人进展期和稳定期外周血淋巴细胞的化学发光，同时检测血浆相关性介质环磷酸腺苷（ｃＡＭＰ）、环磷酸鸟苷（ｃＧＭＰ）、超氧化物歧化酶（ＳＯＤ）水平。结果显示，活动期肺结核病人淋巴细胞基础发光显著增强，植物血凝素（ＰＨＡ）所诱导的最大发光显著减弱。血浆相关性指标ｃＡＭＰ和ＳＯＤ下降，ｃＧＭＰ上升。上述指标在稳定期肺结核病人已与正常对照无显著差异。结果提示肺结核活动期淋巴细胞预激活水平增高，处过度变态反应状态，激活反应能力下降，细胞免疫功能低下。
|
| 关 键 词： | 结核．肺／病理生理学，淋巴细胞 |
The Change and Significance of Blood Lymphocyte Chemiluminescene in Patients with Pulmonary Tuberculosis |
| |
| Zhou Xiangdong,Yang Zhaoheng,Hong Xin,et al..The Change and Significance of Blood Lymphocyte Chemiluminescene in Patients with Pulmonary Tuberculosis[J].The Journal of The Chinese Antituberculosis Association,1996(2). |
| |
| Authors: | Zhou Xiangdong Yang Zhaoheng Hong Xin |
| |
| Institution: | Third Military Medical Univerisity 630042 |
| |
| Abstract: | The method of PHA induced chemiluminescene(CL) of lymphocyte was used to detect the cell-mediated immune function in patients with pulmonary tuberculosis. The serum cGMP, cAMP and SOD levels were examined at the same time, The results showed that the basic CL of lymphocyte increased obviously in the active stage of pulmonary tuberculosis, but the maximum CL decreased. The serum levels of cAMP and SOD decreased. but cGMP increased. There were no obvious abnormalities of above results in the stable period of pulmonary tuberculosis, The results suggest that the lymphocytes are in the preactive state and have low cellular immune functions. |
| |
| Keywords: | tuberculosis pulmonary/physiopathology lymphocyte |
| 本文献已被 CNKI 等数据库收录！ |
