| 复方甘草酸苷抗乙肝病毒所致肝纤维化的临床疗效观察 |
| |
| 引用本文： | 吴玮,刘春华,王千钧,王晓彬,孙树伦.复方甘草酸苷抗乙肝病毒所致肝纤维化的临床疗效观察[J].中国药房,2006,17(15):1164-1165. |
| |
| 作者姓名： | 吴玮 刘春华 王千钧 王晓彬 孙树伦 |
| |
| 作者单位： | 山东青岛市传染病医院,青岛市,266033 |
| |
| 摘 要： | 目的:观察复方甘草酸苷抗乙肝病毒所致肝纤维化的临床疗效。方法:将118例慢性乙肝患者随机分为A、B组,A组给予复方甘草酸苷及基础保肝药物治疗,B组仅给予基础保肝药物治疗,均治疗12wk。观察治疗前、后2组血清玻璃酸酶、层粘连蛋白、Ⅲ型前胶原肽、Ⅳ型胶原的变化。结果:治疗后A组4项指标与B组相比均明显降低,具有显著性差异(P<0·05)。结论:复方甘草酸苷是治疗乙肝病毒所致肝纤维化有效药物之一。
|
| 关 键 词： | 复方甘草酸苷 乙肝病毒 肝纤维化 临床疗效 |
| 文章编号： | 1001-0408(2006)15-1164-02 |
| 收稿时间： | 04 5 2006 12:00AM |
| 修稿时间： | 05 10 2006 12:00AM |
Clinical Efficacy of SNMC in the Treatment Hepatic Fibrosis with Hepatitis B Virus |
| |
| WU Wei,LIU Chunhua,WANG Qianjun,WANG Xiaobin,SUN Shulun.Clinical Efficacy of SNMC in the Treatment Hepatic Fibrosis with Hepatitis B Virus[J].China Pharmacy,2006,17(15):1164-1165. |
| |
| Authors: | WU Wei LIU Chunhua WANG Qianjun WANG Xiaobin SUN Shulun |
| |
| Institution: | Qingdao Municipal Infectious Disease Hospital in Shangdong Province,Qingdao 266033,China |
| |
| Abstract: | OBJECTIVE:To study clinical efficacy of Stronger Neo-Minophagen C(SNMC)in the treatment patients with hepatic fibrosis caused by hepatitis B virus.METHODS:118chronic HB patients were divided into2groups randomly,patients in group A received SNMC and basic treatment,in group B received basic treatment,all for12weeks,4marks of hepatic fibrosis(hyaluronic acid,laminin,typeⅢprocollagen peptide,typeⅣcollagen)were determined before and after treat-ment.RESULTS:Compared with group B,4marks of hepatic fibrosis were obviously reduced in group A after treatment,which were significantly differences between2groups(P<0.05).CONCLUSIONS:SNMC may be one of clinical practical value in tr_ eatment hepatic fibrosis caused by hepatitis B virus. |
| |
| Keywords: | Stronger Neo - Minophagen C Hepatitis B virus Hepatic fibrosis Clinical efficacy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
