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藏药独一味化学成分的研究
引用本文:张爱军,任凤霞,赵毅民.藏药独一味化学成分的研究[J].中国药学杂志,2011,46(2):102-104.
作者姓名:张爱军  任凤霞  赵毅民
作者单位:军事医学科学院毒物药物研究所,北京 100850
摘    要: 目的 研究独一味(Lamiophlomis rotate地上部分的化学成分。方法 利用色谱技术分离化学成分,并根据理化性质和波谱数据鉴定化合物结构。结果 从乙酸乙酯部位分离鉴定了9个化合物,分别为山栀苷甲酯(1,6,7-二羟基香豆素(2,咖啡酸(3、3,4-二羟基苯甲酸(4,芹菜素-7-O-β-D-(-6″-p-香豆酰基-葡萄糖苷(5,丁香酸(6,木犀草素(7,连翘酯苷 B(8,花蕊酯苷(9。结论 化合物2~6为首次从独一味中分离得到。

关 键 词:独一味  6  7-二羟基香豆素  芹菜素-7-O-β-D-(-6″-p-香豆酰基-葡萄糖苷  丁香酸  化学成分
收稿时间:2011-11-11;

Study on the Chemical Constituents of Tibetan Folk Medicine Lamiophlomis rotate
ZHANG Ai-jun,REN Feng-xia,ZHAO Yi-min.Study on the Chemical Constituents of Tibetan Folk Medicine Lamiophlomis rotate[J].Chinese Pharmaceutical Journal,2011,46(2):102-104.
Authors:ZHANG Ai-jun  REN Feng-xia  ZHAO Yi-min
Institution:Institute of Pharmacology and Toxicology,Academy of Military Medical Science,Beijing 100850, China
Abstract:OBJECTIVE To study the chemical constituents of the aerial parts of Tibetan folk medicine Lamiophlomis rotate. METHODS Chemical compounds were extracted and isolated by diverse chromatography and identified by spectroscopic analysis. RESULTS Compounds were isolated and identified as shanzhiganin-1-O-β-D-glucopyranoside methyl ester(1,6,7-dihydroxycoumarin(2,caffeic acid(3,3,4-dihydroxyhenzoic acid(4,apigenin-7-O-β-D-(-6″-p-coumaroyl-glucoside(5,syringic acid(6,luteolin(7,forsythoside B(8,verbascoside(9. CONCLUSION Compounds 2-6 were obtained from Lamiophlomis rotate for the first time.
Keywords: Lamiophlomis rotate" target="_blank">Lamiophlomis rotate')" href="#"> Lamiophlomis rotate  6  7-dihydroxycoumarin  apigenin-7-O-β-D-(-6″-p-coumaroyl-glucoside" target="_blank">O-β-D-(-6″-p-coumaroyl-glucoside')" href="#">apigenin-7-O-β-D-(-6″-p-coumaroyl-glucoside  syringic acid  chemical constituent
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