莫西沙星致不良反应165例分析

摘 要 目的:探讨莫西沙星所致不良反应特点及相关因素，为临床合理用药提供参考。方法：在鼓楼医院2008年5月6日～2013年5月6日上报的不良反应报表中，检索由莫西沙星引起的不良反应，对患者用药情况、性别、年龄、不良反应表现等方面进行统计分析。结果：检索到莫西沙星引起的不良反应165例，其中口服莫西沙星片所致不良反应35例，莫西沙星针剂130例，涉及消化系统、神经系统、心血管系统等系统。结论：临床应重视莫西沙星发生的不良反应，用药时注意患者的临床表现，监测患者肝、肾功能。

Analysis of 165 Adverse Drug Reactions of Moxifloxacin

ABSTRACT Objective::To analyze the adverse drug reactions caused by moxifloxacin to provide a rationale of clinical drug safety. Methods::The incidences of ADRs by propofol injection reported in the Nanjing Drum Tower Hospital from May 6,2008 to May 6, 2013 were collected. A statistical analysis based on medication, gender, age and clinical manifestation was conducted. Results::165 cases of adverse drug reaction were collected. Of all the screened cases, ADRs caused through the oral route were 35 and ADRs through the intravenous route were 130. 165 ADRs were involved in several systems such as digestive system, nervous system , cardio vascular system and so on. Conclusion::Clinical physicians should pay more attention to the patients and ensure patients' safety after moxifloxacin injection was administered. It is necessary to closely observe the laboratory examination of their blood system and to monitor their liver and kidney functions.