ZTE-MRA与TOF-MRA对脑动脉狭窄诊断价值对比研究

目的 探讨零回波时间磁共振血管成像(zero echo time MR angiography,ZTE-MRA)及时间飞跃法磁共振血管成像(time of fight MR angiography,TOF-MRA)的图像质量以及对脑动脉狭窄诊断的价值.材料与方法 纳入19例拟诊断为脑动脉狭窄的患者,同时进行ZTE-MR...

Compared study of the cerebral artery stenosis assessed by ZTE-MRA and TOF-MRA

Objective:To compare the image quality and the diagnostic value of zero-echo-time MR angiography(ZTE-MRA)and time-of-flight MR angiography(TOF-MRA)in the evaluation of cerebral artery stenosis.Materials and Methods:Nineteen cases of cerebral artery stenosis were examined by ZTE-MRA and TOF-MRA at the same time.DSA examination was conducted within one week of MRA examination,to evaluate the accuracy,reliability and specificity of ZTE MRA and TOF-MRA.Results:Among the images obtained by ZTE-MRA and TOF-MRA,the proportion of the images with good score was 84%and 74%.There was no significant difference in the image quality score between the two methods(P>0.05).The average SNR of ZTE-MRA and TOF-MRA were 14.2 and 19.4,respectively.The rank sum test of the two groups of independent samples showed no statistical difference(P>0.05).Based on the diagnosis of cerebral artery stenosis,the sensitivity and specificity of ZTE-MRA were 100%and 98%.The sensitivity and specificity of TOF-MRA in the diagnosis of cerebral arterial stenosis were 85%and 96%,respectively.Compared the consistency of TOF-MRA and DSA,the Kappa value was 0.776,indicating a good consistency between the two.The accuracy rate of grade 1—2 and grade 3—4 arterial stenosis diagnosed by ZTE-MRA was 57%and 81%.Among the TOF-MRA,the accuracy rate of grade 1—2 and grade 3—4 arterial stenosis was 46%and 31%.There was no statistical difference between the two methods in the diagnosis of grade 1—2 arterial stenosis(P>0.05),and there was statistical difference between the two methods in the diagnosis of grade 3—4 arterial stenosis(P<0.05).Conclusions:ZTE-MRA had comparative image quality with TOF-MRA.There was no significant difference between the two methods in the diagnosis of grade 1—2 cerebral arterial stenosis.ZTE-MRA had high value in the diagnosis of grade 3—4 cerebral artery stenosis,accuracy is higher than TOF-MRA.