羟基磷灰石涂层种植体—骨界面的生物力学研究

本项研究选用氧化铝作为种植体基体．在850℃和1050℃下分别在其表面烧结羟基磷灰石(简称HA)．制成HA1和HA2涂层种植体．以纯钛作对照。狗股骨穿皮质种植1、3、6个月后取材，行顶出试验．并对测试后的破坏断面行扫描电镜观察。结果发现：两种HA涂层种植体具有较好的生物力学性能．能在种植早期加速新骨形成、钙化，达到较高的界面结合强度；涂层种植体在顶出试验后．断裂发生在涂层材料内，而纯钛则发生在种植体—骨组织界面；涂层种植体的界面力学性能和烧结温度有关．HA2涂层种植体在各种植程期的界面结合强度均高于HA1涂层种植体。

A biomechanical investigation of Ha-coated ceramic implant]

Two samples of Ha-coated ceramic implants of which sintering temperatures were 850 degrees centigrade,1050 degrees centigrade respectively,were prepared.Pure titanium implant of the same size was accomplished using a transcortical implant model in adult Mongrel dogs.Follow-up periods were 1,3 and 6 months.The results in vivo were evaluated using push-out tests and scanning electron microscope.There were significant differences in push-coated ceramic implants and pure titanium implants,especially for the 1 and 3 months follow-up period.SEM investigation of the interface after push-out test showed for the HA-coated ceramic implants to be fractured in the coating layer and for the Ti-implant to be fractured at the implant-bone interface.