| 玉屏风散对咳嗽变异型哮喘缓解期患者免疫功能的影响 |
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| 引用本文： | 张瑜,张忠德,张溪.玉屏风散对咳嗽变异型哮喘缓解期患者免疫功能的影响[J].广州中医药大学学报,2009,26(6):517-519. |
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| 作者姓名： | 张瑜 张忠德 张溪 |
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| 作者单位： | 广州中医药大学第二附属医院,广东,广州,510120 |
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| 摘 要： | 目的]观察玉屏风散对咳嗽变异型哮喘(CVA)缓解期患者免疫球蛋白E(IgE)及T淋巴细胞亚群CD4+、CD8+等免疫功能的影响.方法]将74例患者随机分为治疗组36例和对照组38例,治疗组予以玉屏风散口服(药物组成:黄芪、白术、防风),对照组予以安慰剂口服,连服8周.观察两组患者治疗前后血清IgE及外周血CD4+、CD8+的变化情况.结果]治疗组治疗后IgE、CD4+水平显著降低(P<0.01),CD8+水平显著升高(P<0.01),CD4+/CD8+显著下降(P<0.01),而对照组治疗前后各项指标均无显著变化(P>0.05).治疗后两组间比较,各项指标差异均有显著性意义(P<0.05或P<0.01).结论]玉屏风散可能通过调节T淋巴细胞亚群和降低血清IgE水平,从而抑制气道炎症,降低气道高反应性,增强人体抗病能力.改善CVA缓解期患者的免疫功能.
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| 关 键 词： | 咳嗽变异型哮喘/中药疗法 玉屏风散/治疗应用 免疫球蛋白E/血液 T淋巴细胞亚群/血液 |
Effect of Yupingfeng Powder on Immune Function in Cough-variant Asthma Patients at Remission Stage |
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| ZHANG Yu,ZHANG Zhongde,ZHANG Xi.Effect of Yupingfeng Powder on Immune Function in Cough-variant Asthma Patients at Remission Stage[J].Journal of Guangzhou University of Traditional Chinese Medicine,2009,26(6):517-519. |
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| Authors: | ZHANG Yu ZHANG Zhongde ZHANG Xi |
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| Institution: | ZHANG Yu,ZHANG Zhongde,ZHANG Xi(The Second Affiliated Hospital,Guangzhou University of TCM,Guangzhou 510120 Guangdong,China) |
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| Abstract: | Objective To observe the effect of Yupingfeng Powder(YP) on IgE level and T lymphocyte subpopulations of CD4+ and CD8+ in cough-variant asthma patients at remission stage.Methods Seventy-four cough-variant asthma(CVA) patients at remission stage were randomized into two groups.The treatment group(N=36) received oral use of YP and the control group(N=38) received oral use of placebo,the treatment lasting 8 weeks.The changes of serum IgE level and T lymphocyte subpopulations of CD4+ and CD8+ were observed bef... |
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| Keywords: | COUGH-VARIANT ASTHMA/TCD therapy YUPINGFENG POWDER/therapeutic use IMMUNOGLOBULIN E/blood T LYMPHOCYTE SUBPOPULATIONS/blood |
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