| 枸杞多糖对去势雌性大鼠骨质疏松影响的研究 |
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| 引用本文： | 王彦明,王一农. 枸杞多糖对去势雌性大鼠骨质疏松影响的研究[J]. 宁夏医学杂志, 2009, 31(6): 497-498 |
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| 作者姓名： | 王彦明 王一农 |
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| 作者单位： | 宁夏医科大学,宁夏,银川,750004;宁夏自治区人民医院,宁夏,银川,750021 |
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| 摘 要： | 目的研究枸杞多糖（LBP）对去势雌性大鼠骨质疏松的影响。方法选用2月龄成年雌性SD实验大鼠50只，随机分为假手术组、去势＋生理盐水组、去势＋枸杞多糖高剂量组、去势＋枸杞多糖低剂量组、去势＋己烯雌酚组等5组，每组10只。术后各组常规饲养10周后给药干预，12周后行股骨干重测量、骨矿密度检查并观察骨的形态学改变。结果与去势＋生理盐水组相比，去势＋枸杞多糖高剂量组、去势＋低剂量组均能增加去势雌性SD大鼠股骨干重、骨密度值，两组骨小梁结构较完整、连续性较好、吸收陷窝少。结论枸杞多糖对成年去势雌性大鼠骨质疏松有明显的骨质改善作用。
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| 关 键 词： | 枸杞多糖 大鼠 骨质疏松 影响 |
An experimental study of LBP for osteroporosis in adult oxariectomized femal rats |
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| WANG Yan-ming,WANG Yi-nong. An experimental study of LBP for osteroporosis in adult oxariectomized femal rats[J]. Ningxia Medical Journal, 2009, 31(6): 497-498 |
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| Authors: | WANG Yan-ming WANG Yi-nong |
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| Affiliation: | Ningxia Medical University;Yinchuan 750004;China |
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| Abstract: | Objective To study the effects of lycium barbarum polysaccharides(LBP) on adult rats after ovariectomy.Methods 50 female SD rats(two-month-old) were randomly divided into 5 groups: sham operated group;ovariectomiced+normal saline group;ovariectomiced+high dose LBP group;ovariectomiced +low dose LBP group and ovariectomiced+Diethylstilbestrol group.They were fed 10 weeks and then took drug for 12 weeks.We examined the femur BMD,weight of dry femur and morphology of every rat.Rusults Comparing with the ovarie... |
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| Keywords: | Lycium barbarum polysaccharides （ LBP ） Rats Osteroporosis Effect |
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