| 间充质干细胞在移植中的作用 |
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| 引用本文： | 唐晶晶,林艳娟.间充质干细胞在移植中的作用[J].白血病．淋巴瘤,2009,18(6):373-376. |
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| 作者姓名： | 唐晶晶 林艳娟 |
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| 作者单位： | 福建医科大学附属协和医院血液科,福州,350001 |
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| 摘 要： | 间充质干细胞（MSC）是一类具有高度自我更新及多向分化潜能的组织干细胞，易于在体外扩增，在造血干细胞移植（HSCT）及其他系统的移植中发挥重要的作用。详细阐述了MSC支持造血、促进植入，调节免疫及减轻移植后的移植物抗宿主病（GVHD）等方面的功能及机制，并对其在临床上的进一步应用提出建议与展望。
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| 关 键 词： | 造血干细胞移植 间质干细胞 移植物抗宿主病 |
| 收稿时间： | 2008-11-14; |
Effect of mesenchymal stem cell in transplantation |
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| TANG Jing-jing,LIN Yan-juan.Effect of mesenchymal stem cell in transplantation[J].Journal of Leukemia & Lymphoma,2009,18(6):373-376. |
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| Authors: | TANG Jing-jing LIN Yan-juan |
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| Abstract: | Mesenchymal stem cell(MSC) is a kind of tissue stem cell having a characteristics of high self-renewal and multipotency. It is tended to be separated in vitro and play an important role in hematopoietic stem cell transplantation and transplantation of other systems. This article described mesenchymal stem cell's function and mechanism on supporting hematopoiesis, enhancing implantation,adjusting immunity and alleviating graft versus host disease (GVHD) in transplantation and also give some advices and experties about its further application. |
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| Keywords: | Hematopoietic stem cell transplantation Mesenchymal stem cells Graft versus host disease |
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