急性心肌梗死患者合并抑郁状况及相关因素分析

目的了解急性心肌梗死3个月以上患者合并抑郁的状况，探讨其相关因素。方法采用电话回访的方式，应用Zung氏抑郁自评量表（SDS），对从本院心内监护入院后出院3-18个月的确诊急性心肌梗死的患者共105例进行问卷调查。结果急性心肌梗死后患者抑郁的发病率是21．9％，单因素分析显示抑郁及非抑郁患者在年龄、既往有高血压病史、出院后发生过心绞痛等方面的差异有统计学意义（P〈0．05）。通过多因素分析显示年龄与急性心肌梗死后抑郁的发生相关（OR．=1．067，95％可信区间1．002—1．137），将年龄与抑郁总分进行相关分析显示二者呈正相关（r=0．439，P〈0．01），年龄越大，抑郁程度越严重。结论急性心肌梗死后患者抑郁发生率较高，年龄是抑郁发生的重要危险因素。

Depression state and relevant factors of patients with acute myocardial infarction

Objective To investigate depression state in patients after acute myocardial inffarction for more than 3 months and analyze the relevant factors.Methods The Zung SDS and general data questionnaire were systematically applied by to the 105 patients after acute myocardial infarction for 3 ～ 18 months by telephone visit.Results Among patients after acute myocardial infarction for more than 3 months,the incidence of depression was 21.9％.Age,history of hypertension,and occurrence of angina after discharges were different in the depression and non-depression patients after myocardial infraction on univariate analysis ( P ＜ 0.05 ).Multiple logistic regression analysis identified age as an independent depression predictor after acute myocardial infraction for more than 3 months ( OR =1.067,95％ CI:1.002 - 1.137),and the incidence of depression were positively associated with age of patients by correction analysis (r =0.439,P =0.000).Conclusions Patients after acute myocardial infarction for long time were still susceptible to depression.Age was the independent risk factor of depression for patients with long term after acute myocardial infraction.