青少年攻击行为与内分泌因素关系的研究

目的:探讨青年攻击行为发生的生物基础,为攻击行为的干预提供科学依据。方法:随机抽取有攻击行为的20名初中生作为病例,选择性别、年龄、年级、性发育等级和家庭经济状况相同的无攻击行为学生作为对照进行1∶1配对研究。采用放射免疫分析法(Radioimmunoassay,RIA)测定病例组和对照组青少年唾液中皮质醇(CORT)、睾酮(T)、催乳素(PRL)、生长激素(GH)含量。结果:男、女有攻击行为青少年睾酮水平明显高于无攻击行为青少年(P<0.05),男性有攻击行为青少年皮质醇水平明显低于无攻击行为青少年(P<0.05),催乳素、生长激素水平两组比较均无显著性差异。男生攻击性与皮质醇浓度呈负相关(P<0.05),女生攻击性与睾酮浓度呈正相关(P<0.01)。皮质醇是男性青少年攻击行为倾向的预测因子,其水平越高,男生攻击性越小。结论:皮质醇、睾酮是影响青少年攻击性的内分泌因素,青少年的攻击行为的发生和发展与内分泌激素具有密切的关系。

Study on the relationship between adolescents'''' aggressive behavior and incretion factors

Objective:To explore the incretion factors which influence adolescents' aggressive behavior,and to provide the theoretical foundation for the prevention of aggression.Methods:Salivary of cortisol(CORT),testosterone(T),prolactin(PRL),growth hormone(GH) were measured with Radioimmunoassay(RIA) in 20 aggressive students and 20 non-aggressive students matched for the same gender,age,grade,stage of pubertal development,economic condition of family.Results:Significant higher T levels were found in male and female students with aggressive behavior(P<0.05),boys with aggressive behavior exhibited lower level of!salivary CORT(P<0.05).There were no significant differences in PRL and OH between aggressive group and non-aggressive group.Correlation analysis revealed a negative relationship in boys between CORT and aggressive and a positive relationship in girls between T and aggression.Multiple linear regression analysis demonstrated that CORT was the predictive factor of aggression of adolescent boys,the higher CORT level was,the less aggression of boys was.Conclusion:CORT and T are the incretion factorswhich affect adolescent aggression.The aggressive behavior of adolescents is related with incretion hormones.