| 动态浊度法测定葛根素注射液中的细菌内毒素 |
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| 引用本文： | 阎凌霄,萧珍,党全训.动态浊度法测定葛根素注射液中的细菌内毒素[J].中国医院药学杂志,2003,23(10):601-602. |
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| 作者姓名： | 阎凌霄 萧珍 党全训 |
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| 作者单位： | 陕西省药品检验所,陕西,西安,710061 |
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| 摘 要： | 目的：建立葛根素注射液中细菌内毒素含量的动态浊度检测方法。方法：通过干扰试验，确定葛根素注射液中细菌内毒素鲎法检测的不干扰浓度。结果：葛根素注射液稀释80倍时的添加细菌内毒素回收率为83％，对鲎试剂无干扰作用。结论：动态浊度法可用于葛根素注射液中细菌内毒素的定量检测。
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| 关 键 词： | 葛根素注射液 动态浊度法 细菌内毒素 |
| 文章编号： | 1001-5213(2003)10-0601-02 |
| 修稿时间： | 2002年5月13日 |
Quantitative measurement of bacterial endotoxin in puerarin injection by kinetic turbidimetric limulus test |
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| YAN Ling-Xiao,XIAO Zhen,DANG Quan-Xun.Quantitative measurement of bacterial endotoxin in puerarin injection by kinetic turbidimetric limulus test[J].Chinese Journal of Hospital Pharmacy,2003,23(10):601-602. |
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| Authors: | YAN Ling-Xiao XIAO Zhen DANG Quan-Xun |
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| Abstract: | OBJECTIVE To establish a method for determination of bacterial endotoxin in puerarin injection by kinetic turbidimetric limulus test.METHODS The testing concentration was selected by interfering experiment.RESULTS When puerarin injection was diluted 80 times the recovery of bacterial endotoxin that was added to the injection was 83%, therefore, at this concentration, there was no interfering affection in limulus test.CONCLUSIONS Kinetic turbidlimulus test can be used to determine quantitatively bacterial endotoxin in puerarin injection. |
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| Keywords: | puerarin injection kinetic turbidimetric limulus test bacterial endotoxin |
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