| 国产低分子肝素钙用于血液透析的抗凝作用 |
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| 引用本文： | 卞维静,谭昭,赵丽.国产低分子肝素钙用于血液透析的抗凝作用[J].中日友好医院学报,1999,13(1):33-36. |
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| 作者姓名： | 卞维静 谭昭 赵丽 |
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| 作者单位： | 友好血液净化中心 |
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| 摘 要： | 目的：验证国产低分子肝素钙（立迈青）用于血液透析（血透）抗凝的疗效和安全性。方法：１５例患者作自身前后交叉对照观察，每例患者各使用立迈青或法安明（低分子肝素钠）进行血透５次，于血透开始时静脉推注立迈青或法安明５０００抗ＦＸａＩＵ，不用维持量。结果：２组患者顺利完成血透各７５例次；透析器容量（ＢＣＶ）减少率、透析１ｈ尿素即刻清除率、白陶土部分凝血活酶时间、血小板及抗ＦＸａ活性等２组间均无显著性差异（Ｐ＞００５）。结论：立迈青作为血透抗凝剂的疗效和安全性与法安明一致。
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| 关 键 词： | 肾功能衰竭.慢性 低分子肝素 血液透析 |
LOW MOLECULAR WEIGHT HEPARIN HOME MADE FOR ANTICOAGULATION DURING
HEMODIALYSIS(HD) |
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| Bian Weijing,Tan Zhao,Zhao Li,et al.LOW MOLECULAR WEIGHT HEPARIN HOME MADE FOR ANTICOAGULATION DURING
HEMODIALYSIS(HD)[J].Journal of China-Japan Friendship Hospital,1999,13(1):33-36. |
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| Authors: | Bian Weijing Tan Zhao Zhao Li et al |
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| Institution: | Friendship Center of Blood
Purification |
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| Abstract: | Objective:To compare the efficacy and safety of home made low
molecular weight heparin(Livaracine) with that of Fragmin.Methods:Fifteen hemodialysis
patients were studied in a radomized crossover fashion.All patients were randomized
into Livaracine and Fragmin in five times HD.Livaracine or Fragmin was given at the
initiation of hemodialysis in a single bolus dose of 5 000 anti FXa IU without
maintanent dose.Results:Seventy five dialysis procedures with either Livaracine or
Fragmin were performed successfully;blood compartment volume of dialyzers,1 hour
clearance of urea,activated partial thromboplastin time,blood platelets count,anti FXa
levels were comparable between these two groups( P >0 05).Conclusion:Livaracine was
effective and safe like as Fragmin. |
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| Keywords: | kidney failure chronic low molecular weight heparin hemodialysis |
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