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唾液富组氨酸阳离子多肽的研究进展
引用本文:苗燕,郝玉庆. 唾液富组氨酸阳离子多肽的研究进展[J]. 国际口腔医学杂志, 2007, 34(4): 271-274
作者姓名:苗燕  郝玉庆
作者单位:口腔生物医学工程教育部重点实验室,四川大学,四川,成都,610041;口腔生物医学工程教育部重点实验室,四川大学,四川,成都,610041
摘    要:人体唾液腺分泌的富组氨酸阳离子多肽与口腔健康关系密切,从20世纪80年代初发现唾液富组氨酸阳离子多肽以来,学者们对其进行了大量的研究,研究结果证实唾液富组氨酸阳离子多肽对口腔真菌、龋病和牙周相关细菌都有广谱抗菌活性.本文就有关唾液富组氨酸阳离子多肽的种类和来源、生物学活性、作用机制的研究进展作一综述.

关 键 词:富组氨酸阳离子多肽  生物学活性  作用机制
修稿时间:2006-06-152007-01-16

Research progress of salivary histidine-rich cationic polypeptides
MIAO Yan,HAO Yu-qing. Research progress of salivary histidine-rich cationic polypeptides[J]. Journal of International Stomatology, 2007, 34(4): 271-274
Authors:MIAO Yan  HAO Yu-qing
Affiliation:Key. Laboratory of Oral Biomedical Engineering of Ministry of Education, Sichuan University, Chengdu 610041, China
Abstract:Histidine-rich cationic polypeptides(HRPs) from human salivary glands have intimate relationship with buccal health. Scholars did much research about histidine-rich cationic polypeptides since 80s of the 20th century, which showed that it had broad-spectrum antibacterial activity on oral fungi and cariogenic bacteria and periodontal pathogens. The article reviewed several aspects of HRPs, which included its kinds, origins, biological activities and mechanisms.
Keywords:histidine-rich cationic polypeptides   biological activities  mechanism
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