| 锌抗石英体外的溶血作用 |
| |
| 引用本文： | 胡天锡 陆志英. 锌抗石英体外的溶血作用[J]. 中国药理学与毒理学杂志, 1989, 3(1): 53-56 |
| |
| 作者姓名： | 胡天锡 陆志英 |
| |
| 作者单位： | 上海劳动卫生职业病研究所，上海劳动卫生职业病研究所，上海劳动卫生职业病研究所 上海 200003，上海 200003，上海 200003 |
| |
| 摘 要： | 本文观察锌对石英溶血的抑制作用。石英对RBC膜有很强的破坏能力,当RBC悬液中加入Zn~(2+),浓度从0.08μmol/ml起,石英的溶血作用受到抑制。本文进一步说明Zn~(2+)对RBC的保护作用以作用于RBC膜的可能性较大,扫描电镜观察表明石英能使人RBC失去原有形态结构,加有Zn~(2+)的RBC,再加石英后,细胞形态完整。
|
| 关 键 词： | 锌 石英 溶血作用 红细胞 扫描电镜 |
Protective effect of zinc on hemolysis induced by quartz in vitro |
| |
| HU Tian-xi,LU Zhi-ing,SHI Da-zhen. Protective effect of zinc on hemolysis induced by quartz in vitro[J]. Chinese Journal of Pharmacology and Toxicology, 1989, 3(1): 53-56 |
| |
| Authors: | HU Tian-xi LU Zhi-ing SHI Da-zhen |
| |
| Abstract: | It is well known that quartz can strongly destroy the membrane of ery-throcyte and induce hemolysis.In this article the results showed that 4.6 mg/ml quartz caused breaking of 50% erythrocytes and 0.08μmol/ml or more zinc inhibited the hemolysis.There was an apparent correlation between dose and protective effect on hemolysis.It was also identified by morphological observation using electron micrograph.Zn2+ may react with the surface substances of ery-throcyte and prevent from hemolysis. |
| |
| Keywords: | zinc quartz hemolysis effect erythrocyte scanning electron micrograph |
| 本文献已被 CNKI 维普 等数据库收录！ |
