伴与不伴注意缺陷多动障碍的抽动秽语综合征患儿动态脑电图的对照研究

目的　探讨伴与不伴注意缺陷多动障碍（ＡＤＨＤ） 的抽动秽语综合征（ＴＳ） 患儿间脑电图的差异。方法　对８６ 例伴与不伴ＡＤＨＤ 的ＴＳ患儿进行２４ ｈ 动态脑电图（ＡＥＥＧ） 监测。结果　伴ＡＤＨＤ的ＴＳ组（４０ 例）ＡＥＥＧ异常率为７５％ ，单纯ＴＳ组（４６ 例） 异常率为３０％ ，２ 组差异有显著性（ Ｐ＜０－０５） ；ＡＥＥＧ异常的主要表现为慢波异常以及癫痫样波。伴ＡＤＨＤ的ＴＳ组的ＡＥＥＧ 局部异常多于广泛异常，且以额叶受累多见；而单纯ＴＳ组则广泛异常多于局部异常。结论　伴与不伴ＡＤＨＤ的ＴＳ患儿在脑电生理学上存在异质性

A study on ambulatory electroencephalogram in children with Tourette syndrome with and without attention deficit hyperactivity disorder

Objective To analyze the difference of EEG in children suffering from Tourette syndrome (TS) with or without attention deficit hyperactivity disorder (ADHD) Methods The 24 hour ambulatory EEG (AEEG) was monitored in 86 children with TS Results AEEG abnormal rate was significantly higher in TS with ADHD (75%) than those without ADHD (30%; P< 0 05) And AEEG abnormality was mainly showed the change of slow wave and the epileptiform discharge AEEG local abnormality was more common than the general abnormality in TS group with ADHD, especially in frontal lobe But the AEEG general abnormality was more common in TS group without ADHD Conclusions TS with and without ADHD may be heterogeneous in neurophysiology